Stromal stress networks underlying phenotypic plasticity and tumor fitness

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Cancer-associated fibroblasts in the single-cell era

Author(s): Dor Lavie, Aviad Ben-Shmuel, Neta Erez, Ruth Scherz-Shouval
Published in: Nature Cancer, Issue 26621347, 2022, Page(s) 793–807, ISSN 2662-1347
Publisher: Springer Nature
DOI: 10.1038/s43018-022-00411-z

Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization

Author(s): Shaashua, L., Mayer, S., Lior, C., Lavon, H., Novoselsky, A., Scherz-Shouval, R.
Published in: Front Cell Dev Biol, 2020, ISSN 2296-634X
Publisher: Frontiers Media SA

Deconstructing tumor heterogeneity: the stromal perspective

Author(s): Vickman, Renee E. Faget, Douglas V. Beachy, Philip Beebe, David Bhowmick, Neil A. Cukierman, Edna Deng, Wu-Min Granneman, James G. Hildesheim, Jeffrey Kalluri, Raghu Lau, Ken S. Lengyel, Ernst Lundeberg, Joakim Moscat, Jorge Nelson, Peter S. Pietras, Kristian Politi, Katerina Puré, Ellen Scherz-Shouval, Ruth Sherman, Mara H. Tuveson, David Weeraratna, Ashani T. White, Richard M. Wong, Melissa H.
Published in: Oncotarget, 2020, ISSN 1949-2553
Publisher: Impact Journals

A framework for advancing our understanding of cancer-associated fibroblasts

Author(s): Erik Sahai; Igor Astsaturov; Edna Cukierman; David G. DeNardo; Mikala Egeblad; Ronald M. Evans; Douglas Fearon; Florian R. Greten; Sunil R. Hingorani; Tony Hunter; Richard O. Hynes; Rakesh K. Jain; Tobias Janowitz; Claus Jorgensen; Alec C. Kimmelman; Mikhail G. Kolonin; Robert G. Maki; R. Scott Powers; Ellen Puré; Daniel C. Ramirez; Ruth Scherz-Shouval; Mara H. Sherman; Sheila Stewart; Thea D. Tl
Published in: Nature reviews. Cancer, vol 20, iss 3, Issue 1, 2020, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.25418/crick.12012540.v1

Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.

Author(s): Nil Grunberg; Meirav Pevsner-Fischer; Tal Goshen-Lago; Judith Diment; Yaniv Stein; Hagar Lavon; Shimrit Mayer; Oshrat Levi-Galibov; Gil Friedman; Yifat Ofir-Birin; LiJyun Syu; Cristina Migliore; Eyal Shimoni; Salomon M. Stemmer; Baruch Brenner; Andrzej A. Dlugosz; David Lyden; Neta Regev-Rudzki; Irit Ben-Aharon; Ruth Scherz-Shouval
Published in: Cancer Res, Issue 1, 2021, ISSN 0008-5472
Publisher: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-20-2756

Expanding the Organismal Proteostasis Network: Linking Systemic Stress Signaling with the Innate Immune Response

Author(s): Jay Miles, Ruth Scherz-Shouval, Patricija van Oosten-Hawle
Published in: Trends in Biochemical Sciences, Issue 44/11, 2019, Page(s) 927-942, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2019.06.009

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

Author(s): Oshrat Levi-Galibov; Hagar Lavon; Rina Wassermann-Dozorets; Meirav Pevsner-Fischer; Shimrit Mayer; Esther Wershof; Yaniv Stein; Lauren E. Brown; Wenhan Zhang; Gil Friedman; Reinat Nevo; Ofra Golani; Lior H. Katz; Lior H. Katz; Rona Yaeger; Ido Laish; Ido Laish; John A. Porco; Erik Sahai; Dror S. Shouval; Dror S. Shouval; David P. Kelsen; Ruth Scherz-Shouval
Published in: Nature Communications, Issue 1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20054-x

Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome

Author(s): Gil Friedman, Oshrat Levi-Galibov, Eyal David, Chamutal Bornstein, Amir Giladi, Maya Dadiani, Avi Mayo, Coral Halperin, Meirav Pevsner-Fischer, Hagar Lavon, Shimrit Mayer, Reinat Nevo, Yaniv Stein, Nora Balint-Lahat, Iris Barshack, H. Raza Ali, Carlos Caldas, Einav Nili-Gal-Yam, Uri Alon, Ido Amit & Ruth Scherz-Shouval
Published in: Nature Cancer, 2020, ISSN 2662-1347
Publisher: Nature Publishing Group

BRCA mutational status shapes the stromalmicroenvironment of pancreatic cancerlinking clusterin expression in cancerassociated fibroblasts with HSF1 signaling

Author(s): Lee Shaashua, Aviad Ben-Shmuel, Meirav Pevsner-Fischer, Gil Friedman, Oshrat Levi-Galibov, Subhiksha Nandakumar, Debra Barki , Reinat Nevo, Lauren E. Brown, Wenhan Zhang, Yaniv Stein, Chen Lior,Han Sang Kim, Linda Bojmar, William R. Jarnagin, Nicolas Lecomte, Shimrit Mayer, Roni Stok, Hend Bishara,Rawand Hamodi, Ephrat Levy-Lahad, Talia Golan, John A. Porco Jr.,Christine A. Iacobuzio-Donahue, Niko
Published in: Nature Communications, Issue 20411723, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34081-3

The Role of HSF1 and the Chaperone Network in the Tumor Microenvironment

Author(s): Nil Grunberg, Oshrat Levi-Galibov, Ruth Scherz-Shouval
Published in: HSF1 and Molecular Chaperones in Biology and Cancer, Issue 1243, 2020, Page(s) 101-111, ISBN 978-3-030-40203-7
Publisher: Springer International Publishing
DOI: 10.1007/978-3-030-40204-4_7

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