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Stromal stress networks underlying phenotypic plasticity and tumor fitness

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Publications

A framework for advancing our understanding of cancer-associated fibroblasts

Author(s): Erik Sahai; Igor Astsaturov; Edna Cukierman; David G. DeNardo; Mikala Egeblad; Ronald M. Evans; Douglas Fearon; Florian R. Greten; Sunil R. Hingorani; Tony Hunter; Richard O. Hynes; Rakesh K. Jain; Tobias Janowitz; Claus Jorgensen; Alec C. Kimmelman; Mikhail G. Kolonin; Robert G. Maki; R. Scott Powers; Ellen Puré; Daniel C. Ramirez; Ruth Scherz-Shouval; Mara H. Sherman; Sheila Stewart; Thea D. Tl
Published in: Nature reviews. Cancer, vol 20, iss 3, 1, 2020, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.25418/crick.12012540.v1

Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.

Author(s): Nil Grunberg; Meirav Pevsner-Fischer; Tal Goshen-Lago; Judith Diment; Yaniv Stein; Hagar Lavon; Shimrit Mayer; Oshrat Levi-Galibov; Gil Friedman; Yifat Ofir-Birin; LiJyun Syu; Cristina Migliore; Eyal Shimoni; Salomon M. Stemmer; Baruch Brenner; Andrzej A. Dlugosz; David Lyden; Neta Regev-Rudzki; Irit Ben-Aharon; Ruth Scherz-Shouval
Published in: Cancer Res, 1, 2021, ISSN 0008-5472
Publisher: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-20-2756

Expanding the Organismal Proteostasis Network: Linking Systemic Stress Signaling with the Innate Immune Response

Author(s): Jay Miles, Ruth Scherz-Shouval, Patricija van Oosten-Hawle
Published in: Trends in Biochemical Sciences, 44/11, 2019, Page(s) 927-942, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2019.06.009

A framework for advancing our understanding of cancer-associated fibroblasts

Author(s): Erik Sahai, Igor Astsaturov, Edna Cukierman, David G. DeNardo, Mikala Egeblad, Ronald M. Evans, Douglas Fearon, Florian R. Greten, Sunil R. Hingorani, Tony Hunter, Richard O. Hynes, Rakesh K. Jain, Tobias Janowitz, Claus Jorgensen, Alec C. Kimmelman, Mikhail G. Kolonin, Robert G. Maki, R. Scott Powers, Ellen Puré, Daniel C. Ramirez, Ruth Scherz-Shouval, Mara H. Sherman, Sheila Stewart, Thea D. Tl
Published in: Nature Reviews Cancer, 20/3, 2020, Page(s) 174-186, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.1038/s41568-019-0238-1

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

Author(s): Oshrat Levi-Galibov; Hagar Lavon; Rina Wassermann-Dozorets; Meirav Pevsner-Fischer; Shimrit Mayer; Esther Wershof; Yaniv Stein; Lauren E. Brown; Wenhan Zhang; Gil Friedman; Reinat Nevo; Ofra Golani; Lior H. Katz; Lior H. Katz; Rona Yaeger; Ido Laish; Ido Laish; John A. Porco; Erik Sahai; Dror S. Shouval; Dror S. Shouval; David P. Kelsen; Ruth Scherz-Shouval
Published in: Nature Communications, 1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20054-x

Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome

Author(s): Gil Friedman, Oshrat Levi-Galibov, Eyal David, Chamutal Bornstein, Amir Giladi, Maya Dadiani, Avi Mayo, Coral Halperin, Meirav Pevsner-Fischer, Hagar Lavon, Shimrit Mayer, Reinat Nevo, Yaniv Stein, Nora Balint-Lahat, Iris Barshack, H. Raza Ali, Carlos Caldas, Einav Nili-Gal-Yam, Uri Alon, Ido Amit & Ruth Scherz-Shouval
Published in: Nature Cancer, 2020, ISSN 2662-1347
Publisher: Nature Publishing Group

The Role of HSF1 and the Chaperone Network in the Tumor Microenvironment

Author(s): Nil Grunberg, Oshrat Levi-Galibov, Ruth Scherz-Shouval
Published in: HSF1 and Molecular Chaperones in Biology and Cancer, 1243, 2020, Page(s) 101-111, ISBN 978-3-030-40203-7
Publisher: Springer International Publishing
DOI: 10.1007/978-3-030-40204-4_7