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Evolutionary biology of human and great ape brain development in cerebral organoids

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Publications

Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output

Author(s): Stefano L. Giandomenico, Susanna B. Mierau, George M. Gibbons, Lea M. D. Wenger, Laura Masullo, Timothy Sit, Magdalena Sutcliffe, Jerome Boulanger, Marco Tripodi, Emmanuel Derivery, Ole Paulsen, András Lakatos, Madeline A. Lancaster
Published in: Nature Neuroscience, 22/4, 2019, Page(s) 669-679, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-019-0350-2

An early cell shape transition drives evolutionary expansion of the human forebrain

Author(s): Silvia Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena Sutcliffe, Erlend S. Riis, Paula Freire-Pritchett, Iva Kelava, Stephanie Wunderlich, Ulrich Martin, Gregory A. Wray, Kate McDole, Madeline A. Lancaster
Published in: Cell, 184/8, 2021, Page(s) 2084-2102.e19, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.02.050

Disease modelling in human organoids

Author(s): Madeline A. Lancaster, Meritxell Huch
Published in: Disease Models & Mechanisms, 12/7, 2019, Page(s) dmm039347, ISSN 1754-8403
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dmm.039347

Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development

Author(s): Stefano L. Giandomenico, Magdalena Sutcliffe, Madeline A. Lancaster
Published in: Nature Protocols, 16/2, 2021, Page(s) 579-602, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-020-00433-w

Human CNS barrier-forming organoids with cerebrospinal fluid production

Author(s): Laura Pellegrini, Claudia Bonfio, Jessica Chadwick, Farida Begum, Mark Skehel, Madeline A. Lancaster
Published in: Science, 369/6500, 2020, Page(s) eaaz5626, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaz5626