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Structural differences in mRNA translation machineries between eukaryotic pathogens and their mammalian hosts

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Publications

The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism

Author(s): Irina S. Abaeva, Quentin Vicens, Anthony Bochler, Heddy Soufari, Angelita Simonetti, Tatyana V. Pestova, Yaser Hashem, Christopher U.T. Hellen
Published in: Cell Reports, Issue 33/10, 2020, Page(s) 108476, ISSN 2211-1247
DOI: 10.1016/j.celrep.2020.108476

Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis

Author(s): Heddy Soufari, Florent Waltz, Camila Parrot, Stéphanie Durrieu-Gaillard, Anthony Bochler, Lauriane Kuhn, Marie Sissler, Yaser Hashem
Published in: Proceedings of the National Academy of Sciences, Issue 117/47, 2020, Page(s) 29851-29861, ISSN 0027-8424
DOI: 10.1073/pnas.2011301117

Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts

Author(s): Anthony Bochler, Jailson Brito Querido, Terezie Prilepskaja, Heddy Soufari, Angelita Simonetti, Mayara Lucia Del Cistia, Lauriane Kuhn, Aline Rimoldi Ribeiro, Leoš Shivaya Valášek, Yaser Hashem
Published in: Cell Reports, Issue 33/12, 2020, Page(s) 108534, ISSN 2211-1247
DOI: 10.1016/j.celrep.2020.108534

Structural Insights into the Mammalian Late-Stage Initiation Complexes

Author(s): Angelita Simonetti, Ewelina Guca, Anthony Bochler, Lauriane Kuhn, Yaser Hashem
Published in: Cell Reports, Issue 31/1, 2020, Page(s) 107497, ISSN 2211-1247
DOI: 10.1016/j.celrep.2020.03.061

The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process

Author(s): Yaser Hashem, Joachim Frank
Published in: Annual Review of Biophysics, Issue 47/1, 2018, Page(s) 125-151, ISSN 1936-122X
DOI: 10.1146/annurev-biophys-070816-034034

Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM

Author(s): Heddy Soufari, Camila Parrot, Lauriane Kuhn, Florent Waltz, Yaser Hashem
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-18814-w

Cryo-EM structure of the RNA-rich plant mitochondrial ribosome

Author(s): Florent Waltz, Heddy Soufari, Anthony Bochler, Philippe Giegé, Yaser Hashem
Published in: Nature Plants, Issue 6/4, 2020, Page(s) 377-383, ISSN 2055-0278
DOI: 10.1038/s41477-020-0631-5

Major structural rearrangements of the canonical eukaryotic translation initiation complex

Author(s): Ewelina Guca, Yaser Hashem
Published in: Current Opinion in Structural Biology, Issue 53, 2018, Page(s) 151-158, ISSN 0959-440X
DOI: 10.1016/j.sbi.2018.08.006

Specificities of the plant mitochondrial translation apparatus

Author(s): Florent Waltz, Nicolas Corre, Yaser Hashem, Philippe Giegé
Published in: Mitochondrion, Issue 53, 2020, Page(s) 30-37, ISSN 1567-7249
DOI: 10.1016/j.mito.2020.04.008