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A novel cost-efficient bioreactor to accelerate growth of valuable plant roots for nutraceuticals, pharmaceuticals cosmetics

Objective

From the 391,000 known species, 18,000 have documented medicinal effect and only 150 are industrially cultivated. Their active principles are extracted from wild or cultivated plants, but the production of these compounds is not sufficient to meet the growing market demand. New sustainable production methods include in-vitro cultivation in bioreactors. However, the main limiting factor is the plant biomass growth rate (e.g. state of the art bubble column bioreactors only reach a doubling time of 20-30 days for ginseng roots). Existing bioreactors are therefore unable to produce at an economically viable level sufficient amounts of biomass and active molecules except for rare applications with very high added value (e.g. pharmaceuticals).
The project develops a novel bioreactor technology enabling a 2x faster biomass growth and a 2-3x boost in active compound elicitation level. Root bioreactors have been so far designed by pharmaceutical engineers without cost considerations as they target high value application. Our team, coming from a food biotech background, has been able to design low-cost bioreactors compatible with high-volume production where costs can be divided by a factor of 10 to target lower value applications such as nutraceuticals. The project initially focuses on the development of a 30 ton/year pilot plant for ginseng roots, a market of 25,000 ton/year currently dominated by US and Asian producers. In addition, the technology has been validated for 29 other root varieties and has the potential to support in-vitro cultivation of any plant root, covering numerous applications in nutraceuticals, pharmaceuticals, cosmetics, fragrances, pest-control, phyto-protection and food additives, among others.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2016-2017

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Coordinator

BOTALYS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
QUAI DES USINES 8
7800 ATH
Belgium

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région wallonne Prov. Hainaut Arr. Ath
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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