Objective
3D cell culture and 3D Bioprinting have become crucial to the development of health and life science research. 3D cell culture has enabled more accurate cell screening, drug and biosensor discovery, tissue engineering, and development of cell lines. One of the major challenges to culturing complex tissues is producing detailed matrix morphologies with optimised pore size, mechanical properties and biocompatibility. Many of the bioink 3D matrices under development do not sufficiently address the physical (mechanical properties), chemical and biological (cell-matrix interactions) complexity required for sucessful 3D culture.
PGD have developed an eight amino acid sequence peptide that self-assembles and forms a hydrogel in the presence of a salt solution. This platform technology is commerically available for 3D culture or tissue engineering research and can be purchased as a liquid or spray. PGD are now investigating the feasibility of producing a bioink. PGD will produce a bioink and disposable mixing chamber that can be 3D printed and support cell viability. For additive manufacturing to break through in the life sciences and pharma industry, a complete package must be provided, including ready to use inks that are true 3D ECM mimics and compatible with processing methods. They must not impede staining/assays or optical/electrochemical detection of cells. At present, there is no bioink on the market that is suitable for large scale use in the pharmaceutical and life science industries.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences clinical medicine oncology breast cancer
- medical and health sciences health sciences personalized medicine
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
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H2020-EU.3.1.3. - Treating and managing disease
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2016-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
SK10 4TG CHESHIRE
United Kingdom
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.