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Scanner for novel chemical reactions

Objective

Funded by the ERC-Starting Grant COMBIPATTERNING, we have developed a novel nanolayer-based synthesis based on patterning different materials with laser radiation in form of a pan-cake spots in array format. Our synthesis robot can do it for many different materials, for >40.000 spots per glass slide, in exactly defined stoichiometries, and for <200 € costs. The robot uses short laser pulses to transfer <1ng “punched-out” material per spot from a donor foil to a synthesis slide. Then, the reactants embedded in the nano thin polymer pan-cake spots can mix with each other and thus undergo chemical reactions by heating the synthesis slide. Due to the large progress in MALDI imaging and the fluorescent scanners, the results of the reactions can be analyzed in the same array format. The masses found by MALDI imaging in some spots might help us to identify unknown chemical reactions. We believe that the nanolayer-based synthesis developed by us might be a basis for future chemistry stations linking scientists and accelerating their studies to screen for novel chemical reactions in a high throughput manner. Instead of studying the interaction between reactants in a single test glass, the chemists will just spin-coat their educts on microscope slides and supply them together with a file for desired reactant combinations to the server - chemical reaction scanner. Therefore, we want to verify the innovation potential of the nanolayer-based synthesis that should find a market where a novel synthesis strategy on combining novel building blocks should be developed, especially, in the field of novel bioactive chemicals and fluorophores.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2017-PoC

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Host institution

KARLSRUHER INSTITUT FUER TECHNOLOGIE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 149 875,00
Address
KAISERSTRASSE 12
76131 Karlsruhe
Germany

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Region
Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 149 875,00

Beneficiaries (1)

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