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PoC in-office device for identifying individuals at high risk of Osteoporosis and osteoporotic fracture

Objective

As a consequence of the ageing of the society, osteoporosis (literally “porous bone”) and its complications is becoming more and more prevalent, making the bone disease a health priority in many parts of the world. Currently osteoporosis is commonly known as a “silent killer” disease. Usually osteoporosis manifests itself in a drastic manner, i.e. through fracture of the osteoporotic bone in the affected individual. Until now little or no measures for prevention or early detection of this disease are taken, because no simple, yet sufficiently precise or sensitive tools for early detection of individuals at risk of osteoporosis are available. The overall objective of the currently proposed PoCOsteo project therefore is the development, clinical validation and preparation for commercialisation of a Point-of-Care tool for bone disease (a.o. osteoporisis) prevention, detection and treatment. To realize this objective a balanced consortium of 5 research partners and 3 SME’s has been brought together, and a well considered workplan devised. Two TRL3 technologies for individual proteomic and genomic electrochemical sensors, available from 2 consortium partners will form the base of the developments. The sensors will be further optimised, combined in a single microfluidic cartridge and integrated in a complete and independent point-of-care bone health assessment tool. The tool will consequently be clinically validated in 2 hospitals (Graz and Tehran), and a business plan for a commercial start-up company wil be prepared for the intended valorisation of the technical and medical activities. The aim is to reach a TRL6 / TRL7 for the complete tool and for the combined microfluidci cartridges. The project will be supported and advised by the IOF, the International Osteoporosis Foundation, which is the main global alliance of patient societies, research organizations, healthcare professionals and international companies working to promote bone, muscle and joint health.

Call for proposal

H2020-NMBP-X-KET-2017
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Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITEIT GENT
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 995 018,75

Participants (7)

UNIVERSITAT ROVIRA I VIRGILI
Spain
EU contribution
€ 601 291,25
Address
Carrer De Escorxador
43003 Tarragona
Activity type
Higher or Secondary Education Establishments
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 397 847,50
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
MICROLIQUID SL
Spain
EU contribution
€ 323 750
Address
Avenida Uribarri 19-1 Saiolan
20500 Arrasate Mondragon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LABMAN AUTOMATION LIMITED
United Kingdom
EU contribution
€ 795 972,50
Address
Seamer Hill Stokesley
TS9 5NQ Middlesbrough Cleveland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MEDIZINISCHE UNIVERSITAT GRAZ
Austria
EU contribution
€ 355 937,50
Address
Auenbruggerplatz 2
8036 Graz
Activity type
Higher or Secondary Education Establishments
TEHRAN UNIVERSITY OF MEDICAL SCIENCES
Iran
EU contribution
€ 361 875
Address
Office Of Vice Chancellor For Global Strategies An International Affairs No 21 Dameshgh St Vali E Asr Ave
1416753955 Tehran
Activity type
Higher or Secondary Education Establishments
FUNDICO BVBA
Belgium
EU contribution
€ 172 500
Address
Gruuthuselaan 19
8020 Oostkamp
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)