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Mechanisms of stem cell population dynamics and reprogramming

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Publications

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

Author(s): Christine S. Kim, Xiaolei Ding, Kira Allmeroth, Leah C. Biggs, Olivia I. Kolenc, Nina L’Hoest, Carlos Andrés Chacón-Martínez, Christian Edlich-Muth, Patrick Giavalisco, Kyle P. Quinn, Martin S. Denzel, Sabine A. Eming, Sara A. Wickström
Published in: Cell Metabolism, Issue 32/4, 2020, Page(s) 629-642.e8, ISSN 1550-4131
DOI: 10.1016/j.cmet.2020.08.011

Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage

Author(s): Michele M. Nava, Yekaterina A. Miroshnikova, Leah C. Biggs, Daniel B. Whitefield, Franziska Metge, Jorge Boucas, Helena Vihinen, Eija Jokitalo, Xinping Li, Juan Manuel García Arcos, Bernd Hoffmann, Rudolf Merkel, Carien M. Niessen, Kris Noel Dahl, Sara A. Wickström
Published in: Cell, Issue 181/4, 2020, Page(s) 800-817.e22, ISSN 0092-8674
DOI: 10.1016/j.cell.2020.03.052

Epigenetic gene regulation, chromatin structure, and force-induced chromatin remodelling in epidermal development and homeostasis

Author(s): Yekaterina A Miroshnikova, Idan Cohen, Elena Ezhkova, Sara A Wickström
Published in: Current Opinion in Genetics & Development, Issue 55, 2019, Page(s) 46-51, ISSN 0959-437X
DOI: 10.1016/j.gde.2019.04.014

Mechanical Forces in the Skin: Roles in Tissue Architecture, Stability, and Function

Author(s): Leah C. Biggs, Christine S. Kim, Yekaterina A. Miroshnikova, Sara A. Wickström
Published in: Journal of Investigative Dermatology, 2019, ISSN 0022-202X
DOI: 10.1016/j.jid.2019.06.137

Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells

Author(s): Hui-Ling Ou, Christine S. Kim, Simon Uszkoreit, Sara A. Wickström, Björn Schumacher
Published in: Developmental Cell, Issue 50/2, 2019, Page(s) 167-183.e8, ISSN 1534-5807
DOI: 10.1016/j.devcel.2019.06.012