Feeling Polarity: Integrating intracellular mechanics and forces for a biophysical understanding of epithelial polarity

Publications

Peer reviewed articles (15)

Self-organization: the fundament of cell biology

Author(s): Roland Wedlich-Söldner and Timo Betz
Published in: Phil. Trans. R. Soc. B, 373 81747), 2018, Page(s) 20170103, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2017.0103

Cortical cell stiffness is independent of substrate mechanics

Author(s): Johannes Rheinlaender, Andrea Dimitracopoulos, Bernhard Wallmeyer, Nils M. Kronenberg, Kevin J. Chalut, Malte C. Gather, Timo Betz, Guillaume Charras, Kristian Franze
Published in: Nature Materials, 19/9, 2020, Page(s) 1019-1025, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-020-0684-x

Intracellular softening and increased viscoelastic fluidity during division

Author(s): Hurst S., Vos B., Brandt M., Betz T.
Published in: Nature Physics, 17, 2021, Page(s) 1270-1276, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-021-01368-z

Fluctuations of a Membrane Nanotube Covered with an Actin Sleeve.

Author(s): Allard, A., Valentino, F., Sykes, C., Betz, T., Campillo, C.
Published in: Phys Rev. E., 102(5), 2020, Page(s) 052402, ISSN 2470-0053
Publisher: American Physics Society
DOI: 10.1103/physreve.102.052402

Actin modulates shape and mechanics of tubular membranes

Author(s): A. Allard, M. Bouzid, T. Betz, C. Simon, M. Abou-Ghali, J. Lemière, F. Valentino, J. Manzi, F. Brochard-Wyart, K. Guevorkian, J. Plastino, M. Lenz, C. Campillo, C. Sykes
Published in: Science Advances, 6/17, 2020, Page(s) eaaz3050, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.aaz3050

Pressure Drives Rapid Burst-Like Coordinated Cellular Motion from 3D Cancer Aggregates

Author(s): Raghuraman, S., Schubert, A.-S., Bröker, S., Jurado, A., Müller, A., Brandt, M., Vos, B.E., Hofemeier, A.D., Abbasi, F., Stehling, M., Wittkowski, R., Ivaska, J., Betz, T.
Published in: Advanved Science, 9, 2022, Page(s) 2270037, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202270037

E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

Author(s): Cecilia Grimaldi, Isabel Schumacher, Aleix Boquet-Pujadas, Katsiaryna Tarbashevich, Bart Eduard Vos, Jan Bandemer, Jan Schick, Anne Aalto, Jean-Christophe Olivo-Marin, Timo Betz, Erez Raz
Published in: Nature Communications, 11, 2020, Page(s) 5397, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19114-z

Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D

Author(s): Long, H., Vos, B.E., Betz, T., Baker, B.M., Trappmann, B.,
Published in: Advanced Science, 2022, Page(s) 2105325, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202105325

Microchip based microrheology via Acoustic Force Spectroscopy shows that endothelial cell mechanics follows a fractional viscoelastic model

Author(s): Alfred Nguyen, Matthias Brandt, Timo Betz
Published in: Lab on a Chip, 10, 2021, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0lc01135e

Designing a high-resolution, LEGO-based microscope for an educational setting

Author(s): Vos BE, Betz Blesa E, Betz T.
Published in: The Biophysicist, 2, 2021, Page(s) 29-40, ISSN 2578-6970
Publisher: Allen Press
DOI: 10.35459/tbp.2021.000191

Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis

Author(s): Hofemeier, A.D., Limon, T., Muenker, T.M., Wallmeyer, B., Jurado, A., Afshar, M.E., Ebrahimi, M., Tsukanov, R., Oleksiievets, N., Enderlein, J., Gilbert, P.M., Betz, T.
Published in: eLife, 10, 2021, Page(s) e60145, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.60145

Using migrating cells as probes to illuminate features in live embryonic tissues

Author(s): Gross-Thebing, S*., Truszkowski, L*., Tenbrinck, D*+., Sánchez-Iranzo, H., Camelo, C., Westerich, K.J., Singh, A., Paul Maier, P., Prengel, J., Lange, P., Hüwel, J., Gaede, F., Sasse, R., Vos, E.B., Betz, T., Matis, M., Prevedel, R., Luschnig, S., Diz-Muñoz, A., Burger, M., Raz, E
Published in: Science Advances, (6) 49,, 2020, Page(s) eabc5546., ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abc5546

Unveiling the Active Nature of Living-Membrane Fluctuations and Mechanics

Author(s): Hervé Turlier, Timo Betz
Published in: Annual Review of Condensed Matter Physics, 10/1, 2019, Page(s) 213-232, ISSN 1947-5454
Publisher: Annual Reviews Inc.
DOI: 10.1146/annurev-conmatphys-031218-013757

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Author(s): Andreu, I., Falcones, B., Hurst, S., Chahare, N., Quiroga, X., Roux, A.-L.L., Kechagia, Z., Beedle, A.E.M., Elósegui-Artola, A., Trepat, X., Farré, R., Betz, T., Almendros, I., Roca-Cusachs, P.
Published in: Nature Communications, 12, 2021, Page(s) 4229, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24383-3

Active diffusion in oocytes nonspecifically centers large objects during prophase I and meiosis I

Author(s): Alexandra Colin, Gaëlle Letort, Nitzan Razin, Maria Almonacid, Wylie Ahmed, Timo Betz, Marie-Emilie Terret, Nir S. Gov, Raphaël Voituriez, Zoher Gueroui, Marie-Hélène Verlhac
Published in: The Journal of Cell Biology, 219/3, 2020, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201908195