Investigating the role of the long noncoding transcriptome in chromatin replication

Project Information

NonChroRep

Grant agreement ID: 771425

DOI 10.3030/771425

Project closed

EC signature date 7 February 2018

Start date 1 April 2018

End date 31 March 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
Spain

Publications

Peer reviewed articles (6)

Gene regulation by long non-coding RNAs and its biological functions

Author(s): Luisa Statello, Chun-Jie Guo, Ling-Ling Chen, and Maite Huarte
Published in: NATURE REVIEWS MOLECULAR CELL BIOLOGY, Issue 22 (2), 2021, Page(s) 96-118, ISSN 1471-0072
Publisher: Nature Publishing Group
DOI: 10.1038/s41580-020-00315-9

The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors

Author(s): Luisa Statello, José Miguel Fernandez-Justel, Jovanna González, Marta Montes, Alessia Ranieri, Enrique Goñi, Aina M Mas, Maite Huarte
Published in: NATURE COMMUNICATIONS, Issue 15, 1, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45183-5.

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

Author(s): Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14623-3

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins

Author(s): Aina Maria Mas; Enrique Goñi; Igor Ruiz de los Mozos; Aida Arcas; Luisa Statello; Jovanna González; Lorea Blázquez; Wei Ting Chelsea Lee; Dipika Gupta; Álvaro Sejas; Shoko Hoshina; Alexandros Armaos; Gian Gaetano Tartaglia; Shou Waga; Jernej Ule; Eli Rothenberg; María Gómez; Maite Huarte
Published in: Nature Communications, Issue 14, 1, 2023, Page(s) 1-19, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-40105-3

Long Noncoding RNA Signatures as Cancer Biomarkers

Author(s): Aina M Mas, Maite Huarte
Published in: JOURNAL OF CLINICAL ONCOLOGY, Issue 41, 16, 2023, Page(s) 3059+, ISSN 0732-183X
Publisher: American Society of Clinical Oncology
DOI: 10.1200/jco.23.00381

Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion

Author(s): Alejandro Athie, Francesco P. Marchese, Jovanna González, Teresa Lozano, Ivan Raimondi, Prasanna Kumar Juvvuna, Amaya Abad, Oskar Marin-Bejar, Jacques Serizay, Dannys Martínez, Daniel Ajona, Maria Jose Pajares, Juan Sandoval, Luis M. Montuenga, Chandrasekhar Kanduri, Juan J. Lasarte, Maite Huarte
Published in: Journal of Cell Biology, Issue 219/9, 2020, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201908078