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Patient-specific treatment for Parkinson's disease using reprogrammed skin cells

Publications

Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons

Author(s): Marcella Birtele, Yogita Sharma, Srisaiyini Kidnapillai, Shong Lau, Thomas B. Stoker, Roger A. Barker, Daniella Rylander Ottosson, Janelle Drouin‐Ouellet, Malin Parmar
Published in: FEBS Letters, Issue 593/23, 2019, Page(s) 3370-3380, ISSN 0014-5793
DOI: 10.1002/1873-3468.13612

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Author(s): Katarína Tiklová, Åsa K. Björklund, Laura Lahti, Alessandro Fiorenzano, Sara Nolbrant, Linda Gillberg, Nikolaos Volakakis, Chika Yokota, Markus M. Hilscher, Thomas Hauling, Fredrik Holmström, Eliza Joodmardi, Mats Nilsson, Malin Parmar, Thomas Perlmann
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-08453-1

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

Author(s): Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K. Björklund, Yogita Sharma, Andreas Heuer, Linda Gillberg, Deirdre B. Hoban, Tiago Cardoso, Andrew F. Adler, Marcella Birtele, Hilda Lundén-Miguel, Nikolaos Volakakis, Agnete Kirkeby, Thomas Perlmann, Malin Parmar
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-16225-5

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

Author(s): Deirdre B. Hoban, Shelby Shrigley, Bengt Mattsson, Ludivine S. Breger, Ulla Jarl, Tiago Cardoso, Jenny Nelander Wahlestedt, Kelvin C. Luk, Anders Björklund, Malin Parmar
Published in: Proceedings of the National Academy of Sciences, 2020, Page(s) 202001305, ISSN 0027-8424
DOI: 10.1073/pnas.2001305117