Exploration below the tip of the microtubule

Project Information

ICEBERG

Grant agreement ID: 771599

DOI 10.3030/771599

Project closed

EC signature date 13 June 2018

Start date 1 October 2018

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 998 227,00

EU contribution € 1 998 227,00

Coordinated by

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France

Publications

Peer reviewed articles (12)

Stress fibres are embedded in a contractile cortical network

Author(s): Timothée Vignaud, Calina Copos, Christophe Leterrier, Mauricio Toro-Nahuelpan, Qingzong Tseng, Julia Mahamid, Laurent Blanchoin, Alex Mogilner, Manuel Théry, Laetitia Kurzawa
Published in: Nature Materials, Issue 20/3, 2021, Page(s) 410-420, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-020-00825-z

Self-repair protects microtubules from destruction by molecular motors

Author(s): Sarah Triclin, Daisuke Inoue, Jérémie Gaillard, Zaw Min Htet, Morgan E. DeSantis, Didier Portran, Emmanuel Derivery, Charlotte Aumeier, Laura Schaedel, Karin John, Christophe Leterrier, Samara L. Reck-Peterson, Laurent Blanchoin, Manuel Théry
Published in: Nature Materials, Issue 20/6, 2021, Page(s) 883-891, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-020-00905-0

Microtubule self-repair

Author(s): Manuel Théry, Laurent Blanchoin
Published in: Current Opinion in Cell Biology, Issue 68, 2021, Page(s) 144-154, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2020.10.012

Microtubules control nuclear shape and gene expression during early stages of hematopoietic differentiation

Author(s): Stefan Biedzinski, Gökçe Agsu, Benoit Vianay, Marc Delord, Laurent Blanchoin, Jerome Larghero, Lionel Faivre, Manuel Théry, Stéphane Brunet
Published in: The EMBO Journal, Issue 39/23, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2019103957

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

Author(s): Ievgenia Pastushenko, Federico Mauri, Yura Song, Florian de Cock, Bob Meeusen, Benjamin Swedlund, Francis Impens, Delphi Van Haver, Matthieu Opitz, Manuel Thery, Yacine Bareche, Gaelle Lapouge, Marjorie Vermeersch, Yves-Rémi Van Eycke, Cédric Balsat, Christine Decaestecker, Youri Sokolow, Sergio Hassid, Alicia Perez-Bustillo, Beatriz Agreda-Moreno, Luis Rios-Buceta, Pedro Jaen, Pedro Redondo, Ra
Published in: Nature, Issue 589/7842, 2021, Page(s) 448-455, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-03046-1

Tailoring cryo-electron microscopy grids by photo-micropatterning for in-cell structural studies

Author(s): Mauricio Toro-Nahuelpan, Ievgeniia Zagoriy, Fabrice Senger, Laurent Blanchoin, Manuel Théry, Julia Mahamid
Published in: Nature Methods, Issue 17/1, 2020, Page(s) 50-54, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-019-0630-5

CLASP Mediates Microtubule Repair by Restricting Lattice Damage and Regulating Tubulin Incorporation

Author(s): Amol Aher, Dipti Rai, Laura Schaedel, Jeremie Gaillard, Karin John, Qingyang Liu, Maarten Altelaar, Laurent Blanchoin, Manuel Thery, Anna Akhmanova
Published in: Current Biology, Issue 30/11, 2020, Page(s) 2175-2183.e6, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2020.03.070

Lattice defects induce microtubule self-renewal

Author(s): Laura Schaedel, Sarah Triclin, Denis Chrétien, Ariane Abrieu, Charlotte Aumeier, Jérémie Gaillard, Laurent Blanchoin, Manuel Théry, Karin John
Published in: Nature Physics, Issue 15/8, 2019, Page(s) 830-838, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-019-0542-4

Spatial integration of mechanical forces by α-actinin establishes actin network symmetry

Author(s): Fabrice Senger, Amandine Pitaval, Hajer Ennomani, Laetitia Kurzawa, Laurent Blanchoin, Manuel Théry
Published in: Journal of Cell Science, Issue 132/22, 2019, Page(s) jcs236604, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.236604

Hematopoietic progenitors polarize in contact with bone marrow stromal cells by engaging CXCR4 receptors.

Author(s): Bessy, Thomas; Souquet, Benoit; Vianay, Benoit; Schaeffer, Alexandre; Jaffredo, Thierry; Larghero, Jerome; Blanchoin, Laurent; Brunet, Stephane; Faivre, Lionel; Thery, Manuel
Published in: The Journal of Cell Biology, Issue 1, 2021, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202005085

Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth

Author(s): Lara Katharina Krüger; Matthieu Gélin; Liang Ji; Carlos Kikuti; Anne Houdusse; Manuel Théry; Laurent Blanchoin; Phong T Tran
Published in: Elife, Issue 1, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/2021.02.17.431708

Acto-myosin network geometry defines centrosome position

Author(s): Ana Joaquina Jimenez, Alexandre Schaeffer, Chiara De Pascalis, Gaëlle Letort, Benoit Vianay, Michel Bornens, Matthieu Piel, Laurent Blanchoin, Manuel Théry
Published in: Current Biology, Issue 31/6, 2021, Page(s) 1206-1220.e5, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2021.01.002

Other (1)

Biophysical properties of intermediate states of EMT outperform both epithelial and mesenchymal states.

Author(s): Yoran Margaron; Yoran Margaron; Tomoaki Nagai; Tomoaki Nagai; Laurent Guyon; Laetitia Kurzawa; Laetitia Kurzawa; Anne-Pierre Morel; Alice Pinheiro; Laurent Blanchoin; Laurent Blanchoin; Fabien Reyal; Alain Puisieux; Manuel Théry; Manuel Théry
Published in: BioRxiv, Issue 1, 2020
Publisher: BioRxiv
DOI: 10.1101/797654