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Exploring the hidden life of African trypanosomes: parasite fat tropism and implications for disease

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan

First version of the Data Management Plan

Publications

Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence

Author(s): Mariana De Niz, Daniela Brás, Marie Ouarné, Mafalda Pedro, Ana M. Nascimento, Lenka Henao Misikova, Claudio A. Franco, Luisa M. Figueiredo
Published in: Cell Reports, Issue 36, 2023, Page(s) 109741, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109741

A long noncoding RNA promotes parasite differentiation in African trypanosomes

Author(s): Fabien Guegan, K. Shanmugha Rajan, Fábio Bento, Daniel Pinto-Neves, Mariana Sequeira, Natalia Gumińska, Seweryn Mroczek, Andrzej Dziembowski, Smadar Cohen-Chalamish, Tirza Doniger, Beathrice Galili, Antonio M. Estévez, Cedric Notredame, Shulamit Michaeli, Luisa M. Figueiredo
Published in: Science Advances, Issue 8, 2024, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn2706

Surgical and intravital microscopy protocol to image Trypanosoma brucei–host interactions in live rodent models

Author(s): Mariana De Niz, Luisa M. Figueiredo
Published in: STAR Protocols, Issue 3, 2024, Page(s) 101450, ISSN 2666-1667
Publisher: Elsevier
DOI: 10.1016/j.xpro.2022.101450

A novel lipase with dual localisation in Trypanosoma brucei

Author(s): S.G. Monic, A. Lamy, M. Thonnus, T. Bizarra-Rebelo, F. Bringaud, T. K. Smith, L. M. Figueiredo, L. Rivière
Published in: Scientific Reports, Issue 12, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-08546-w

Immunopathology and Trypanosoma congolense parasite sequestration cause acute cerebral trypanosomiasis

Author(s): Sara Silva Pereira, Mariana De Niz, Karine Serre, Marie Ouarné, Joana E Coelho, Cláudio A Franco, Luisa M Figueiredo
Published in: eLife, Issue 11, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.77440

Tissue tropism in parasitic diseases

Author(s): Sara Silva Pereira, Sandra Trindade, Mariana De Niz, Luisa M. Figueiredo
Published in: Open Biology, Issue 9/5, 2019, Page(s) 190036, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.190036

Detection of Extravascular <em>Trypanosoma</em> Parasites by Fine Needle Aspiration

Author(s): Tânia Carvalho, Ana Margarida Santos, Luísa M. Figueiredo
Published in: Journal of Visualized Experiments, Issue 150, 2019, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/59798

Slow growing behavior in African trypanosomes during adipose tissue colonization

Author(s): Sandra Trindade, Mariana De Niz, Mariana Costa-Sequeira, Tiago Bizarra-Rebelo, Fábio Bento, Mario Dejung, Marta Valido Narciso, Lara López-Escobar, João Ferreira, Falk Butter, Frédéric Bringaud, Erida Gjini, Luisa M. Figueiredo
Published in: Nature Communications, Issue 13, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34622-w

Adipocyte lipolysis protects mice against Trypanosoma brucei infection

Author(s): Henrique Machado, Peter Hofer, Rudolf Zechner, Terry K. Smith, Luísa M. Figueiredo
Published in: Nature Microbiology, Issue 8, 2023, Page(s) 2020-2032, ISSN 2058-5276
Publisher: Springer
DOI: 10.1038/s41564-023-01496-7

Intravital imaging of host–parasite interactions in skin and adipose tissues

Author(s): Mariana De Niz, Gavin R. Meehan, Nicolas M.B. Brancucci, Matthias Marti, Brice Rotureau, Luisa M. Figueiredo, Friedrich Frischknecht
Published in: Cellular Microbiology, Issue 21/5, 2019, Page(s) e13023, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.13023

Trypanosoma brucei triggers a broad immune response in the adipose tissue

Author(s): Henrique Machado, Tiago Bizarra-Rebelo, Mariana Costa-Sequeira, Sandra Trindade, Tânia Carvalho, Filipa Rijo-Ferreira, Barbara Rentroia-Pacheco, Karine Serre, Luisa M. Figueiredo
Published in: PLOS Pathogens, Issue 17, 2021, Page(s) e1009933, ISSN 1553-7374
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1009933

Cellular microbiology interview—Luisa Figueiredo

Author(s): Luisa Miranda Figueiredo
Published in: Cellular Microbiology, Issue 21/9, 2019, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.13073

Polyreactive Antibodies Bridge Immunity Particles to Pathogen

Author(s): Henrique Machado, Luisa M. Figueiredo
Published in: Trends in Parasitology, Issue 36/10, 2020, Page(s) 804-806, ISSN 1471-4922
Publisher: Elsevier BV
DOI: 10.1016/j.pt.2020.07.012

Longitudinal analysis of adipocytes and liver gene expression during T. brucei infection

Author(s): João Francisco Parraga Ribeiro Colaço
Published in: 2020
Publisher: Universidade de Lisboa

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