Spatiotemporal regulation of localization and replication of M. tuberculosis in human macrophages

Project Information

DynaMO_TB

Grant agreement ID: 772022

DOI 10.3030/772022

EC signature date 30 January 2018

Start date 1 September 2018

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom

Publications

Peer reviewed articles (2)

High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages.

Author(s): Beren Aylan; Laure Botella; Maximiliano G. Gutierrez; Pierre Santucci
Published in: Crossref, Issue 1, 2022, ISSN 2211-5463
Publisher: Elsevier BV
DOI: 10.1002/2211-5463.13537

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Author(s): Claudio Bussi, Tiaan Heunis, Enrica Pellegrino, Elliott M. Bernard, Nourdine Bah, Mariana Silva Dos Santos, Pierre Santucci, Beren Aylan, Angela Rodgers, Antony Fearns, Julia Mitschke, Christopher Moore, James I. MacRae, Maria Greco, Thomas Reinheckel, Matthias Trost & Maximiliano G. Gutierrez
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34632-8

Non-peer reviewed articles (3)

M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

Author(s): Elliott M. Bernard, Antony Fearns, Claudio Bussi, Pierre Santucci, Christopher J. Peddie, Rachel J. Lai, Lucy M. Collinson, Maximiliano G. Gutierrez
Published in: Journal of Cell Science, Issue 134/5, 2021, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.252973

Human stem cell‐based models for studying host‐pathogen interactions

Author(s): Enrica Pellegrino, Maximiliano G. Gutierrez
Published in: Cellular Microbiology, 2021, ISSN 1462-5814
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cmi.13335

Mycobacterium tuberculosis infection of host cells in space and time

Author(s): Claudio Bussi, Maximiliano G Gutierrez
Published in: FEMS Microbiology Reviews, Issue 43/4, 2019, Page(s) 341-361, ISSN 1574-6976
Publisher: Oxford University Press
DOI: 10.1093/femsre/fuz006

Conference proceedings (1)

The metabolic response of human macrophages to Mycobacterium tuberculosis infection

Author(s): C Bussi, M Silva Dos Santos, E M Bernard, P Santucci, J I Macrae, M G Gutierrez
Published in: 10.02 - Tuberculosis, 2020, Page(s) 65
Publisher: European Respiratory Society
DOI: 10.1183/23120541.lsc-2020.65