supracellular contractility of myofibroblasts in gut homeostasis and cancer invasion

Project Information

STARNEL

Grant agreement ID: 772487

DOI

10.3030/772487

Project closed

EC signature date 26 September 2018

Start date 1 October 2018

End date 30 September 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Other (2)

Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature

Author(s): Neda Glisovic, Aleksandra Chikina, Noémie Robil, Sonia Lameiras, Danijela Matic Vignjevic
Published in: BioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.09.627573

Aging and freezing of active nematic dynamics of cancer-associated fibroblasts by fibronectin matrix remodeling

Author(s): Cécile Jacques, Joseph Ackermann, Samuel Bell, Clément Hallopeau, Carlos Perez- Gonzalez, Lakshmi Balasubramaniam, Xavier Trepat, Benoît Ladoux, Ananyo Maitra, Raphael Voituriez, Danijela Matic Vignjevic
Published in: BioRxiv, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.11.22.568216

Peer reviewed articles (9)

Compressive stress triggers fibroblasts spreading over cancer cells to generate carcinoma in situ organization

Author(s): Fabien Bertillot, Laetitia Andrique, Carlos Ureña Martin, Olivier Zajac, Ludmilla de Plater, Michael M. Norton, Aurélien Richard, Kevin Alessandri, Basile G. Gurchenkov, Florian Fage, Atef Asnacios, Christophe Lamaze, Moumita Das, Jean- Léon Maître, Pierre Nassoy, Danijela Matic Vignjevic
Published in: Communications Biology, Issue 7, 2024, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-05883-6

At the right time in the right place: How do luminal gradients position the microbiota along the gut?

Author(s): Aleksandra Chikina, Danijela Matic Vignjevic
Published in: Cells & Development, 2021, Page(s) 203712, ISSN 2667-2901
Publisher: Elsevier
DOI: 10.1016/j.cdev.2021.203712

Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

Author(s): Carlos Pérez-González, Gerardo Ceada, Francesco Greco, Marija Matejčić, Manuel Gómez-González, Natalia Castro, Anghara Menendez, Sohan Kale, Denis Krndija, Andrew G. Clark, Venkata Ram Gannavarapu, Adrián Álvarez-Varela, Pere Roca-Cusachs, Eduard Batlle, Danijela Matic Vignjevic, Marino Arroyo, Xavier Trepat
Published in: Nature Cell Biology, Issue 23, 2023, Page(s) 745-757, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-021-00699-6

Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction

Author(s): Jorge Barbazan, Carlos Pérez-González, Manuel Gómez-González, Mathieu Dedenon, Sophie Richon, Ernest Latorre, Marco Serra, Pascale Mariani, Stéphanie Descroix, Pierre Sens, Xavier Trepat, Danijela Matic Vignjevic
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-42382-4

Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions

Author(s): Marine Verhulsel, Anthony Simon, Moencopi Bernheim-Dennery, Venkata Ram Gannavarapu, Lauriane Gérémie, Davide Ferraro, Denis Krndija, Laurence Talini, Jean-Louis Viovy, Danijela Matic Vignjevic, Stéphanie Descroix
Published in: Lab on a Chip, Issue 21/2, 2021, Page(s) 365-377, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0lc00672f

Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption

Author(s): Aleksandra S. Chikina, Francesca Nadalin, Mathieu Maurin, Mabel San-Roman, Thibault Thomas-Bonafos, Xin V. Li, Sonia Lameiras, Sylvain Baulande, Sandrine Henri, Bernard Malissen, Livia Lacerda Mariano, Jorge Barbazan, J. Magarian Blander, Iliyan D. Iliev, Danijela Matic Vignjevic, Ana-Maria Lennon-Duménil
Published in: Cell, Issue 183/2, 2020, Page(s) 411-428.e16, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.08.048

Self-generated gradients steer collective migration on viscoelastic collagen networks

Author(s): Andrew G. Clark, Ananyo Maitra, Cécile Jacques, Martin Bergert, Carlos Pérez-González, Anthony Simon, Luc Lederer, Alba Diz-Muñoz, Xavier Trepat, Raphaël Voituriez, Danijela Matic Vignjevic
Published in: Nature Materials, Issue 21, 2022, Page(s) 1200-1210, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-022-01259-5

Stand by me: Fibroblasts regulation of the intestinal epithelium during development and homeostasis

Author(s): Neta Felsenthal, Danijela Matic Vignjevic
Published in: Current Opinion in Cell Biology, Issue 78, 2024, Page(s) 102116, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2022.102116

PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance

Author(s): Meryem B. Baghdadi, Ronja M. Houtekamer, Louisiane Perrin, Abilasha Rao-Bhatia, Myles Whelen, Linda Decker, Martin Bergert, Carlos Pérez-Gonzàlez, Réda Bouras, Giacomo Gropplero, Adrian K. H. Loe, Amin Afkhami-Poostchi, Xin Chen, Xi Huang, Stephanie Descroix, Jeffrey L. Wrana, Alba Diz-Muñoz, Martijn Gloerich, Arshad Ayyaz, Danijela Matic Vignjevic, Tae-Hee Kim
Published in: Science, Issue 386, 2024, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adj7615