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SMAll RuminanTs breeding for Efficiency and Resilience

Deliverables

Method for identifying environmental challenge events and assessment of their value for selection for resilience

Longitudinal data is so far not used to infer and report unobserved challenges We will describe a method that from repeated phenotypic data milk yield litter size will identify critical points challenging events such as unobserved infections in the lifespan of animals The method will be able to evaluate and identify superior animals for resilience to such events

A report for optimum contribution to manage diversity at critical regions and to assist mating design to maximise heterozygosity and expression of heterosis and evaluation of level inbreeding rate across genomic regions and their impact on performance

Genomic selection requires genomic management of diversity We will describe a method to first assess critical regions possibly carriers of deleterious recessive mutations and second maximize diversity in particular in those regions using optimal contributions and mate allocation

A report of an improved method to calculate genomic relationship across individuals of different purebred and crossbred populations

Joint multiple breed and crossbred genomic evaluations are not fully developed in small ruminants We will create a method to compute joint genomic relationships across individuals within a single breed across multiple breeds and across all possible crosses in a manner that genomic evaluations can generate the most accurate estimates of breeding values within and across populations profiting the information of all populations

Method for assessing potential bias due to design of cross-validation analysis

Crossvalidation studies in small ruminants may underestimate benefit accuracy and genetic progress of genomic selection due to short size of studies and the use of selected animals We will describe a crossvalidation method that generates meaningful estimates of accuracy and expected genetic progress from genomic selection

First batch of practice abstract for end-users

"The resulting innovative knowledge and easy accessible end-user material from this project will feed into the EIP-AGRI (The agricultural European Innovation Partnership) website for broad dissemination. The end-user material to be produced contains a substantial number of summaries for practitioners in the EIP common format (""practice abstracts""), including the characteristics of the project (e.g. contact details of partners, etc). A full package of practice abstracts will be produced by the project, containing all the outcomes/recommendations which are ready for practice. A ""practice abstract"" is a short summary of around 1000-1500 characters (word count – no spaces; see below) which describes the main information/recommendation/practice that can serve the end-users in their daily practice. Guidance and templates for these practice abstracts are available on the EIP-AGRI web site: http://ec.europa.eu/eip/agriculture/en/content/eip-agri-common-format. A total target number of 10 practice abstracts is foreseen for the project. Five ares expected to be delivered in the first batch. "

Website on line, & communication package

Development and launching of the project website and creation of main communication supports

Publications

Genetic Characterization and Population Connectedness of North American and European Dairy Goats

Author(s): Marc Teissier, Luiz F. Brito, Flavio S. Schenkel, Guido Bruni, Pancrazio Fresi, Beat Bapst, Christèle Robert-Granie and Hélène Larroque
Published in: Frontiers in Genetics, Vol. 13, n°862838, 2022, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2022.862838

The value of genomic relationship matrices for estimating inbreeding.

Author(s): Villanueva B, Fernández A, Saura M, Caballero A, Fernández J, Morales-González E, Toro MA, Pong-Wong R
Published in: Genetics Selection Evolution, 53, 2021, Page(s) 42, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.1186/s12711-021-00635-0

Changes in allele frequencies when different genomic coancestry matrices are used for maintaining genetic diversity.

Author(s): Morales-González E, Fernández J, Pong-Wong R, Toro MA and Villanueva B
Published in: Genetic Selection Evolution, 2021, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.3390/genes12050673

Association Study of Parasite Resistance to Gastrointestinal Nematodes in Corriedale Sheep

Author(s): Carracelas, E.A. Navajas, B. Vera, G. Ciappesoni
Published in: Genes, 13 (9), 2022, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13091548

Removing data and using metafounders alleviates biases for all traits in Lacaune dairy sheep predictions

Author(s): Macedo, F. L., Astruc, J. M., Meuwissen, T. H. E., & Legarra, A.
Published in: Journal of Dairy Science, 105, 2022, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2021-20860

Single- and multiple-breed genomic evaluations for conformation traits in Canadian Alpine and Saanen dairy goats

Author(s): Massender, L. F. Brito, L. Maignel, H. R. Oliveira, M. Jafarikia, C. F. Baes, B. Sullivan, F.S. Schenkel
Published in: Journal of Dairy Science, Vol. 105, issue 7, 2022, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2021-21713

Across-country genetic evaluation of meat sheep from Ireland and the United Kingdom

Author(s): Fitzmaurice, S., Conington, J., McDermott, K., McHugh, N., & Banos, G.
Published in: Journal of Animal Breeding and Genetics, 139, 2022, Page(s) 342– 350, ISSN 6790-4823
Publisher: International Journal of Animal Breeding and Genetics
DOI: 10.1111/jbg.12668

Islands of runs of homozygosity indicate selection signatures in Ovis aries 6 (OAR6) of French dairy sheep

Author(s): Rodríguez-Ramilo S., Reverter A., Legarra A.
Published in: JDS Communications, 2 (3), 2021, Page(s) 132-136, ISSN 2666-9102
Publisher: Elsevier Inc and FASS Inc.
DOI: 10.3168/jdsc.2020-0011

Potentials of using milk performance data and FAMACHA score as indicators for Targeted Selective Treatment in Lacaune dairy sheep in Switzerland

Author(s): K. Schwarz, B, Bapst, M. Holinger, S. Thüer, I. Schleip, S. Werne
Published in: Veterinary Parasitology, 2020, ISSN 0304-4017
Publisher: Elsevier BV
DOI: 10.1016/j.vpoa.2020.100030

Repeatability of health and welfare traits and correlation with performance traits in dairy goat breeds reared under low-input farming systems

Author(s): S. Vouraki, A. Gelasakis, V. Fotiadou, G. Banos, G. Arsenos
Published in: Veterinary Sciences, 9(6), 2022, ISSN 2078-2489
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vetsci9060289

Genomic and pedigree estimation of inbreeding depression for semen traits in the Basco-Béarnaise dairy sheep breed.

Author(s): Antonios S., Rodríguez-Ramilo S., Aguilar I., Astruc J., Legarra A., VITEZICA Z.
Published in: Journal of Dairy Science, 104, 2021, Page(s) 3221-3230, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2020-18761

The cost of host genetic resistance on body condition: Evidence from divergently selected sheep

Author(s): Frédéric Douhard, Andrea B Doeschl‐Wilson, Alexander Corbishley, Adam D Hayward, Didier Marcon, Jean‐Louis Weisbecker, Sophie Aguerre, Léa Bordes, Philippe Jacquiet, Tom N McNeilly, Guillaume Sallé, Carole Moreno
Published in: Evolutionary Applications, vol 15, issue 9, 2022, ISSN 1752-4571
Publisher: Evolutionary applications
DOI: 10.1111/eva.13442

Theoretical and empirical comparisons of expected and realized relationships for the X-chromosome.

Author(s): Druet T., Legarra A.
Published in: Genetics Selection Evolution, 104, 2021, Page(s) 52, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.1186/s12711-020-00570-6

The levels of artificial insemination and missing sire information make genomic selection not always beneficial in meat sheep

Author(s): J. Raoul, J.M. Elsen
Published in: Animal, 2021, ISSN 1751-7311
Publisher: Cambridge University Press
DOI: 10.1016/j.animal.2020.100040

SNP arrays evaluation as tools in genetic improvement in Corriedale sheep in Uruguay

Author(s): Carracelas, E.A. Navajas, B. Vera, G. Ciappesoni
Published in: Agrociencia Uruguay, Vol. 26 n.2, 2022, Page(s) 1-13, ISSN 2730-5066
Publisher: Agronomy School of the University of the Republic (udelar), and the National Institute of Agricultural Research (INIA)
DOI: 10.31285/agro.26.998

Livestock disease resilience: From individual to herd level

Author(s): Doeschl-Wilson A, Knap P.W., Opriessnig T. and More S.J.
Published in: Animal, 15, 2021, Page(s) 100286, ISSN 1751-7311
Publisher: Cambridge University Press
DOI: 10.1016/j.animal.2021.100286

Residual feed intake for Australian Merino sheep estimated in less than 42 days of trial

Author(s): F. Amarilho-Silveira, I. de Barbieri, J. Araujo Cobucia, C. Marques Balconi, G. Ferreira de Ferreira, G. Ciappesoni
Published in: Livestock Science, Vol. 258, 2022, Page(s) 1-12, ISSN 1871-1413
Publisher: Elsevier BV
DOI: 10.1016/j.livsci.2022.104889

Single-Step Genomic Evaluation for Milk Production Traits in Canadian Alpine and Saanen Dairy Goats

Author(s): Massender, L. F. Brito, L. Maignel, H. R. Oliveira, M. Jafarikia, C. F. Baes, B. Sullivan, F.S. Schenkel
Published in: Journal of Dairy Science, Vol. 105, issue. 3, 2022, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2021-20558

Why breed disease-resilient livestock, and how?

Author(s): Knap P.W. and Doeschl-Wilson A
Published in: Genetics Selection Evolution, 52, 2020, Page(s) 60, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.1186/s12711-020-00580-4

Genome-wide analyses reveal a strong association between LEPR gene variants and body fat reserves in ewes

Author(s): Tiphaine Macé, Eliel González‑García, Didier Foulquié, Fabien Carrière, Julien Pradel, Christian Durand, Sebastien Douls, Charlotte Allain, Sara Parisot and Dominique Hazard
Published in: BMC Genomics, (2022) 23:412, 2022, ISSN 1471-2164
Publisher: BioMed Central
DOI: 10.1186/s12864-022-08636-z

Detection of unrecorded environmental challenges in high-frequency recorded traits, and genetic determinism of resilience to challenge, with an application on feed intake in lambs.

Author(s): Garcia-Baccino C. A., MARIE-ETANCELIN C., Tortereau F., Marcon D., Weisbecker J.-L., Legarra A.
Published in: Genetics Selection Evolution, 53, 2021, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.1186/s12711-020-00595-x

Exploring the inclusion of genomic information and metafounders in Latxa dairy sheep genetic evaluations

Author(s): I. Granado-Tajada, A. Legarra, E. Ugarte
Published in: Journal of Dairy Science, 103/7, 2020, Page(s) 6346-6353, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2019-18033

Short communication: Methods to compute genomic inbreeding for ungenotyped individuals

Author(s): A. Legarra, I. Aguilar, J.J. Colleau
Published in: Journal of Dairy Science, 103/4, 2020, Page(s) 3363-3367, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2019-17750

Considerable potential exists to improve lambing performance traits in sheep through breeding

Author(s): N. McHugh, T. Pabiou, E. Wall, K. McDermott, D.P. Berry
Published in: Livestock Science, 235, 2020, Page(s) 104007, ISSN 1871-1413
Publisher: Elsevier BV
DOI: 10.1016/j.livsci.2020.104007

Genetic and genomic studies in ovine mastitis

Author(s): C. Oget, G. Tosser-Klopp, R. Rupp
Published in: Small Ruminant Research, 176, 2019, Page(s) 55-64, ISSN 0921-4488
Publisher: Elsevier BV
DOI: 10.1016/j.smallrumres.2019.05.011

Genetic and nongenetic factors associated with the fate of maiden ewe lambs: slaughtered without ever lambing versus retained for breeding1

Author(s): Noirin McHugh, Thierry Pabiou, Kevin McDermott, Eamon Wall, Donagh P Berry
Published in: Translational Animal Science, 4/1, 2020, Page(s) 242-249, ISSN 2573-2102
Publisher: Oxford University Press on behalf of the American Society of Animal Science
DOI: 10.1093/tas/txz156

Behavior of the Linear Regression method to estimate bias and accuracies with correct and incorrect genetic evaluation models

Author(s): F.L. Macedo, A. Reverter, A. Legarra
Published in: Journal of Dairy Science, 103/1, 2020, Page(s) 529-544, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2019-16603

Selection and drift reduce genetic variation for milk yield in Manech Tête Rousse dairy sheep.

Author(s): Macedo F., Christensen O., Legarra A.
Published in: JDS Communications, 2021, Page(s) 31-34, ISSN 2666-9102
Publisher: Elsevier Inc and FASS Inc.
DOI: 10.3168/jdsc.2020-0010

Inbreeding and effective population size in French dairy sheep: Comparison between genomic and pedigree estimates

Author(s): T. Rodríguez-Ramilo, J. M. Elsen, A. Legarra
Published in: Journal of Dairy Science, 2019, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2018-15405

Genetic and economic benefits of foreign sire contributions to a domestic sheep industry; including an Ireland-New Zealand case study

Author(s): Nicola Fetherstone; Nicola Fetherstone; Fiona S. Hely; Noirin McHugh; Fiona McGovern; P. R. Amer
Published in: Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-15 (2021), 53, 2021, ISSN 1297-9686
Publisher: BioMed Central Ltd
DOI: 10.1186/s12711-020-00594-y

Genetic analyses of live weight and carcass composition traits in purebred Texel, Suffolk and Charollais lambs

Author(s): S. Fitzmaurice, J. Conington, N. Fetherstone, T. Pabiou, K. McDermott, E. Wall, G. Banos, N. McHugh
Published in: Animal, 2020, ISSN 1751-7311
Publisher: Cambridge University Press
DOI: 10.1017/s1751731119002908

Evaluation of the Links between Lamb Feed Efficiency and Rumen and Plasma Metabolomic Data

Author(s): Florian Touitou, Flavie Tortereau, Lydie Bret, Nathalie Marty-Gasset, Didier Marcon and Annabelle Meynadier
Published in: Metabolites, vol 12, issue 4, 2022, ISSN 2078-2489
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/metabo12040304

The correlation of substitution effects across populations and generations in the presence of non-additive functional gene action.

Author(s): Legarra A., Garcia-Baccino C.A., Wientjes Y.C.J., Vitezica Z.G.
Published in: Genetics, Volume 219, Issue 4, 2021, ISSN 1943-2631
Publisher: Genetics Society of America
DOI: 10.1093/genetics/iyab138

A Nonsense Variant in CCDC65 Gene Causes Respiratory Failure Associated with Increased Lamb Mortality in French Lacaune Dairy Sheep

Author(s): Maxime Ben Braiek, Carole Moreno-Romieux, Charlotte Allain, Philippe Bardou, Arnaud Bordes, Frédéric Debat, Cord Drögemüller, Florence Plisson-Petit, David Portes, Julien Sarry, Némuel Tadi, Florent Woloszyn, Stéphane Fabre
Published in: Genes, Vol 13, Issue 1, 2021, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13010045

Identification of homozygous haplotypes carrying putative recessive lethal mutations that compromise fertility traits in French Lacaune dairy sheep

Author(s): M. Ben Braiek, S. Fabre, C. Hoze, J.M. Astruc, C. Moreno-Romieux
Published in: Genetics Selection Evolution, 2021, ISSN 0999-193X
Publisher: BioMed Central
DOI: 10.1186/s12711-021-00634-1

Selection on functional longevity in a commercial population of dairy goats translates into significant differences in longevity in a common farm environment

Author(s): M. Ithurbide, C. Huau, I. Palhière, T. Fassier, N.C. Friggens, R. Rupp
Published in: Journal of Dairy Science, Vol. 105, n. 3, 2022, ISSN 0022-0302
Publisher: American Dairy Science Association
DOI: 10.3168/jds.2021-21222

High genetic correlation for milk yield across Manech and Latxa dairy sheep from France and Spain

Author(s): A. Garcia-Baccino, C. Pineda-Quiroga, J. M. Astruc, E. Ugarte, A. Legarra
Published in: JDS Communication, Vol. 3 Issue 4, 2022, ISSN 2666-9102
Publisher: JDS communications
DOI: 10.3168/jdsc.2021-0195

Repeatability of udder health and welfare traits of semi-extensively reared dairy goats in Greece

Author(s): Sotiria Vouraki, Athanasios I. Gelasakis, Vasileia Fotiadou, Georgios Banos, Georgios Arsenos
Published in: Book of Abstracts of the 72nd Annual Meeting of the European Federation of Animal Science, 2021, Page(s) 272-272, ISSN 1382-6077
Publisher: Wageningen Academic Publishers
DOI: 10.3920/978-90-8686-918-3

Book of Abstracts of the 70th Annual Meeting of the European Federation of Animal Science

Author(s): Scientific Committee
Published in: 2019, ISBN 978-90-8686-339-6
Publisher: Wageningen Academic Publishers
DOI: 10.3920/978-90-8686-890-2

On the accuracy of estimating resilience

Author(s): Ghaderi-Zefreh M, Riggio V, Matika O, Wilson A, Pong-Wong R
Published in: Proceeding of the 71st Annual Meeting of European Federation of Animal Science, 2020
Publisher: .

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