Veterinary Validation of Point-of-Care Detection Instrument

Project Information

VIVALDI

Grant agreement ID: 773422

DOI 10.3030/773422

Project closed

EC signature date 10 October 2017

Start date 1 January 2018

End date 30 April 2022

Funded under

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Total cost € 3 198 508,79

EU contribution € 2 918 817,84

Coordinated by

DANMARKS TEKNISKE UNIVERSITET
Denmark

Objective

In the VIVALDI project the consortium will validate new equipment (the VETPOD platform) for rapid on-site detection of zoonotic pathogens in industrial food and animal production chains.
The coordinator Technical University of Denmark (DTU) has developed the VETPOD platform based on Loop mediated isothermal amplification (LAMP) technology and optical read-out to a user interface, with disposable plastic cartridges (Lab-on-Chip, LOC) that can be adapted to an infinite number of assays for almost all pathogens.
We have a portable LOC system with optical detection: a system with polymeric chip made by injection moulded with multiple (8-32) chambers suitable for rapid online or on site detection of pathogens. The polymer chip with multiple chambers is able to perform LAMP to detect different pathogens at species level from multiple (8-30) samples within 30-60 min.
We want to validate the VETPOD platform for three important zoonotic pathogens: Avian Influenza Virus (AIV) or Highly Pathogenic Avian Influenza Virus (HPAIV), Salmonella spp. and Campylobacter spp. For HPAIV this will include identification of H types (H5 and H7), for Salmonella the identification of the most important serovars S. Enteritidis, S. Typhimurium and S. Dublin, and for Campylobacter species identification of C. jejuni and C. coli.
The validation includes two stages:
1) Validation by national reference laboratories in DK, SE, IT and FR. Each NRL will involve 10 external labs for ring trials.
2) End-user validation at private labs (SMEs) in DE and IT.
The equipment provider will prepare a business plan for sale of the VETPOD system.
The private labs will prepare business plans for using the VETPOD platform for at site animal health detection as well as for online detection of zoonotic pathogens in food and animal production chains.

Fields of science

• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › health sciences › infectious diseases › RNA viruses › influenza
• natural sciences › chemical sciences › polymer sciences
• agricultural sciences › animal and dairy science › domestic animals › animal husbandry
• medical and health sciences › health sciences › public health › epidemiology › zoonosis

Keywords

• Ring trial
• National Reference Laboratories
• Avian Influenza Virus
• Salmonella
• Campylobacter

Programme(s)

• H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme
• H2020-EU.3.2.1.1. - Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience

Topic(s)

• SFS-13-2017 - Validation of diagnostic tools for animal and plant health

Call for proposal

H2020-SFS-2016-2017

See other projects for this call

Sub call

H2020-SFS-2017-1

Funding Scheme

IA - Innovation action

Coordinator

DANMARKS TEKNISKE UNIVERSITET

• Net EU contribution: € 1 442 326,02
• Address: ANKER ENGELUNDS VEJ 101 ; 2800 Kongens Lyngby ; Denmark
• Region: Danmark › Hovedstaden › Københavns omegn
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 1 511 938,56

Participants (7)

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

DIANOVA AS

Participation ended

Denmark

• Net EU contribution: € 48 728,77
• Address: CENTRIFUGEVEJ 371 ; 2800 Kgs Lyngby
• Region: Danmark › Hovedstaden › Københavns omegn
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 69 612,53

STATENS VETERINAERMEDICINSKA ANSTALT

Sweden

• Net EU contribution: € 302 269,65
• Address: Ulls Vaeg 2B ; 75189 Uppsala
• Region: Östra Sverige › Östra Mellansverige › Uppsala län
• Activity type: Research Organisations
• Total cost: € 302 269,65

AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL

France

• Net EU contribution: € 361 051,63
• Address: 14 RUE PIERRE ET MARIE CURIE ; 94700 Maisons Alfort
• Region: Ile-de-France › Ile-de-France › Val-de-Marne
• Activity type: Research Organisations
• Total cost: € 361 051,63

UNIVERSITA DEGLI STUDI DI PARMA

Italy

• Net EU contribution: € 160 558,34
• Address: VIA UNIVERSITA 12 ; 43121 PARMA
• Region: Nord-Est › Emilia-Romagna › Parma
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 160 558,34

ACEL SERVICE SRL

Italy

• Net EU contribution: € 161 253,75
• Address: LANGHIRANO (PR) VIA FANTI D'ITALIA, 9/1 CAP 43013 ; 43013 LANGHIRANO PR
• Region: Nord-Est › Emilia-Romagna › Parma
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 230 362,50

MARTIN FRETTLOH

Germany

• Net EU contribution: € 120 806,88
• Address: SIEGENER STRASSE 27-29 ; 57080 Siegen
• SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes:
  Region
  Nordrhein-Westfalen › Arnsberg › Siegen-Wittgenstein
• Region: Nordrhein-Westfalen › Arnsberg › Siegen-Wittgenstein
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 172 581,25

DNA DIAGNOSTIC A/S

Denmark

• Net EU contribution: € 321 822,80
• Address: VOLDBJERGVEJ 14 ; 8240 Risskov
• Region: Danmark › Midtjylland › Østjylland
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 459 746,86