Objective
Injectable bulking agents have been attempted to treat and manage stress urinary incontinence since the 1990's. But their application has been limited by efficacy, durability, biocompatibility, usability and other issues. Lack of a single, reproducible response from one agent has led to the adoption of several such materials. However, none of those materials can be used as a scaffold for tissue regeneration, they are mostly temporary tissue fillers. Once they degrade, the effectivity is diminished, typically within 6-8 months only. A permanent bulking agent was not successful as it often causes immunological adverse events (such as foreign body granulomas) that limit safety and efficacy. Between 1995-2011 a bovine crosslinked collagen product – Contigen® was used successfully to treat PMSI in dogs, however its production was stopped in 2011. CellFoam™ is a biomaterial scaffold augmentation agent that stimulates the body own cells to build de-novo tissue in place of the biomaterial. Thus, when degraded, a long-term tissue augmentation effect is maintained by urethral remodelling. As such continence is resolved.
The overarching objective of the present feasibility study is to mitigate risks related to subsequent phases of the CellFoam™ innovation project, i.e. the risks associated with the planned industrialization, the commercialization of the solution and post-project exploitation of the results.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- agricultural sciences animal and dairy science domestic animals
- medical and health sciences medical biotechnology tissue engineering
- social sciences political sciences political transitions revolutions
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.1.2. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies
MAIN PROGRAMME
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H2020-EU.2.1.5. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced manufacturing and processing
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H2020-EU.2.1.3. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials
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H2020-EU.2.3.1. - Mainstreaming SME support, especially through a dedicated instrument
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2016-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
30815 KIBUTZ NAHSHOLIM
Israel
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.