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Regenerative Medicine Innovation Crossing - Research and Innovation Staff Exchange in Regenerative Medicine

Deliverables

Biocompatibility reports

Biocompatibility reports

Public Engagement plan

Public Engagement plan

Multifunctional scaffold

Multifunctional scaffold

Blends and composites of selected materials

Blends and composites of selected materials

Safety and toxicity tests

Safety and toxicity tests

Fabrication and characterization of natural biomaterial scaffolds

Fabrication and characterization of natural biomaterial scaffolds

Methods and procedures for biological evaluation of scaffolds

Methods and procedures for biological evaluation of scaffolds

Natural origin materials , with different physicochemical properties and of different origin

Natural origin materials (polysaccharides, proteins, ceramics), with different physicochemical properties and of different origin, suitable for the development of multifunctional biomaterials

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Publications

Exploring the Gelation Mechanisms and Cytocompatibility of Gold (III)-Mediated Regenerated and Thiolated Silk Fibroin Hydrogels

Author(s): Chavee Laomeephol, Helena Ferreira, Supansa Yodmuang, Rui L. Reis, Siriporn Damrongsakkul, Nuno M. Neves
Published in: Biomolecules, 10/3, 2020, Page(s) 466, ISSN 2218-273X
Publisher: Biomolecules
DOI: 10.3390/biom10030466

Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin‐23 Neutralization

Author(s): Ana Cláudia Lima, Cláudia F. Campos, Cristina Cunha, Agostinho Carvalho, Rui L. Reis, Helena Ferreira, Nuno M. Neves
Published in: Advanced Healthcare Materials, 10/2, 2021, Page(s) 2001570, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202001570

A Bio-inspired Multifunctionalized Silk Fibroin

Author(s): Sofia Santi, Ines Mancini, Sandra Dirè, Emanuela Callone, Giorgio Speranza, Nicola Pugno, Claudio Migliaresi, Antonella Motta
Published in: ACS Biomaterials Science & Engineering, 7/2, 2021, Page(s) 507-516, ISSN 2373-9878
Publisher: ACS Biomaterials
DOI: 10.1021/acsbiomaterials.0c01567

Anti-Inflammatory Properties of Injectable Betamethasone-Loaded Tyramine-Modified Gellan Gum/Silk Fibroin Hydrogels

Author(s): Isabel Matos Oliveira, Cristiana Gonçalves, Myeong Eun Shin, Sumi Lee, Rui Luis Reis, Gilson Khang, Joaquim Miguel Oliveira
Published in: Biomolecules, 10/10, 2020, Page(s) 1456, ISSN 2218-273X
Publisher: Biomolecules
DOI: 10.3390/biom10101456

Enzymatically crosslinked tyramine-gellan gum hydrogels as drug delivery system for rheumatoid arthritis treatment

Author(s): Isabel Matos Oliveira, Cristiana Gonçalves, Myeong Eun Shin, Sumi Lee, Rui L. Reis, Gilson Khang, Joaquim Miguel Oliveira
Published in: Drug Delivery and Translational Research, 2020, ISSN 2190-393X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13346-020-00855-9

Dual-functional liposomes for curcumin delivery and accelerating silk fibroin hydrogel formation

Author(s): Chavee Laomeephol, Helena Ferreira, Sorada Kanokpanont, Nuno M. Neves, Hisatoshi Kobayashi, Siriporn Damrongsakkul
Published in: International Journal of Pharmaceutics, 589, 2020, Page(s) 119844, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2020.119844

Processing keratin from camel hair and cashmere with ionic liquids

Author(s): Y. J. Yang, D. Ganbat, P. Aramwit, A. Bucciarelli, J. Chen, C. Migliaresi, A. Motta
Published in: Express Polymer Letters, 13/2, 2019, Page(s) 97-108, ISSN 1788-618X
Publisher: Budapesti Muszaki Egyetem, Department of Polymer Engineering
DOI: 10.3144/expresspolymlett.2019.10

Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation

Author(s): Yuejiao Yang, Gabriele Greco, Devid Maniglio, Barbara Mazzolai, Claudio Migliaresi, Nicola Pugno, Antonella Motta
Published in: Materials Science and Engineering: C, September 13th, 2019, 2019, Page(s) 110197, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2019.110197

Layer‐by‐layer films based on catechol‐modified polysaccharides produced by dip‐ and spin‐coating onto different substrates

Author(s): Ana C. Almeida, Ana C. Vale, Ricardo A. Pires, Rui L. Reis, Natália M. Alves
Published in: Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2019, 2019, Page(s) 1-16, ISSN 1552-4973
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jbm.b.34489

Phospholipid‐induced silk fibroin hydrogels and their potential as cell carriers for tissue regeneration

Author(s): Chavee Laomeephol, Marta Guedes, Helena Ferreira, Rui L. Reis, Sorada Kanokpanont, Siriporn Damrongsakkul, Nuno M. Neves
Published in: Journal of Tissue Engineering and Regenerative Medicine, 31 October 2019, 2019, ISSN 1932-6254
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/term.2982

Amphiphilic copolymers in biomedical applications: Synthesis routes and property control

Author(s): Francesca Perin, Antonella Motta, Devid Maniglio
Published in: Materials Science and Engineering: C, 123, 2021, Page(s) 111952, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2021.111952

Modulating inflammation through the neutralization of Interleukin-6 and tumor necrosis factor-α by biofunctionalized nanoparticles

Author(s): Ana Cláudia Lima, Diana Amorim, Inês Laranjeira, Armando Almeida, Rui L. Reis, Helena Ferreira, Filipa Pinto-Ribeiro, Nuno M. Neves
Published in: Journal of Controlled Release, 331, 2021, Page(s) 491-502, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2021.02.001

Bioactive and adhesive properties of multilayered coatings based on catechol-functionalized chitosan/hyaluronic acid and bioactive glass nanoparticles

Author(s): Ana Catarina Almeida, Ana Catarina Vale, Rui L. Reis, Natália M. Alves
Published in: International Journal of Biological Macromolecules, 157, 2020, Page(s) 119-134, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/j.ijbiomac.2020.04.095