Skip to main content

Soraprazan - a new regenerative therapy for Stargardt's disease

Objective

Soraprazan – a new regenerative therapy for Stargardt’s disease
Abnormal accumulation of lipofuscin in the RPE cells is a hallmark in Stargardt's disease. As lipofuscin cannot be removed from the RPE cells in the eyes neither spontaneously nor with existing therapies, the accumulation of lipofuscin in the RPE cells of the eyes results in the degradation of the RPE cells and consequently in worsening of visual acuity and could lead to blindness. Soraprazan was able to show removal of lipofuscin in RPE cells. Aim of the phase II trial in this project is to evaluate savety and efficacy or orally taken Soraprazan treatment compared to placebo.

Call for proposal

H2020-SC1-2017-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

EBERHARD KARLS UNIVERSITAET TUEBINGEN
Address
Geschwister-scholl-platz
72074 Tuebingen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 467 500

Participants (7)

KATAIRO GMBH
Germany
EU contribution
€ 2 705 000
Address
Lederstr. 21
72127 Kusterdingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING KATHOLIEKE UNIVERSITEIT
Netherlands
EU contribution
€ 319 500
Address
Geert Grooteplein Noord 9
6525 EZ Nijmegen
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 178 222,50
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 252 500
Address
Highfield
SO17 1BJ Southampton
Activity type
Higher or Secondary Education Establishments
OSPEDALE SAN RAFFAELE SRL
Italy
EU contribution
€ 180 171,25
Address
Via Olgettina 60
20132 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SMERUD MEDICAL RESEARCH INTERNATIONAL AS
Norway
EU contribution
€ 1 561 250
Address
Karenslyst Alle 6
0278 Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITATSKLINIKUM BONN
Germany
EU contribution
€ 128 281,25
Address
Venusberg-campus 1
53127 Bonn
Activity type
Higher or Secondary Education Establishments