The innovative method of real-time deformability cytometry can be used to analyze blood samples and compile the “mechanical haemogram” where different types of white blood cells are investigated for their mechanical properties. The information gained from the mechanical haemogram can be used to characterize the state of the immune system and therefore, to monitor the inflammation reaction of the body to an infection. The goal of this proof-of-concept grant was to evaluate the applicability and commercial potential of the mechanical haemogram in sepsis therapy management, still one of the great challenges in modern medicine. While clearly development, adjustment and especially market introduction of diagnostic tests demand immense efforts, resources and time, it is most important to build a strong foundation to start this process. With the funding by the proof-of-concept grant we were able to build this foundation and to conduct research not only on the methodology of the mechanical haemogram but also into the needs and demands of all parts of the health care system that could profit from this test. As a result, we were able to create a business case and identify the key success factors for the road to follow in bringing the mechanical haemogram to market as part of the business strategy of the startup company ZELLMECHANIK DRESDEN GmbH.
