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Development of a Microfluidic Microbial Ecology Device and Mathematical Model to Study Antibiotic Response of Individual Cells

Objective

To discover effective strategies against antimicrobial resistance, a deeper understanding of microbial behaviour in their natural ecologies is crucial. The essential technological bottleneck that has limited our capability to explore this issue is the microenvironment provided by batch culture assays. They are incapable of mimicking natural microhabitats, quantifying individual bacteria, and revealing antibiotic resistance. Therefore, development of a theoretical and experimental framework that mimics the natural microecology of bacteria and measuring their antibiotic response to predict optimum survival strategies will provide valuable tools to investigate bacterial individuality and their changing response to antibiotics in realistic microenvironments.

Coordinator

SABANCI UNIVERSITESI
Net EU contribution
€ 145 845,60
Address
ORTA MAHALLE UNIVERSITE CADDESI N 27 TUZLA
34956 Istanbul
Türkiye

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Region
İstanbul İstanbul İstanbul
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 145 845,60