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Foundations of Geometric Statistics and Their Application in the Life Sciences

Objective

"Invariance under gauge transformation groups provides the natural structure explaining the laws of physics. In life sciences, new mathematical tools are needed to estimate approximate invariance and establish general but approximate laws. Rephrasing Poincaré: a geometry cannot be more true than another, it may just be more convenient, and statisticians must find the most convenient one for their data. At the crossing of geometry and statistics, G-Statistics aims at establishing the mathematical foundations of geometric statistics and exemplifying their impact on selected applications in the life sciences.

So far, mainly Riemannian manifolds and negatively curved metric spaces have been studied. Other geometric structures like quotient spaces, stratified spaces or affine connection spaces naturally arise in applications. G-Statistics will explore ways to unify statistical estimation theories, explaining how the statistical estimations diverges from the Euclidean case in the presence of curvature, singularities, stratification. Beyond classical manifolds, particular emphasis will be put on flags of subspaces in manifolds as they appear to be natural mathematical object to encode hierarchically embedded approximation spaces.

In order to establish geometric statistics as an effective discipline, G-Statistics will propose new mathematical structures and theorems to characterize their properties. It will also implement novel generic algorithms and illustrate the impact of some of their efficient specializations on selected applications in life sciences. Surveying the manifolds of anatomical shapes and forecasting their evolution from databases of medical images is a key problem in computational anatomy requiring dimension reduction in non-linear spaces and Lie groups. By inventing radically new principled estimations methods, we aim at illustrating the power of the methodology and strengthening the ""unreasonable effectiveness of mathematics"" for life sciences."

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-ADG - Advanced Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2017-ADG

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Host institution

INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 183 583,75
Address
DOMAINE DE VOLUCEAU ROCQUENCOURT
78153 Le Chesnay Cedex
France

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Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 2 183 583,75

Beneficiaries (1)

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