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Elucidating Mechanisms of Bladder Cancer Metastasis

Objective

Bladder cancer is the ninth most afflicted cancer in the world which affects people in both developing and developed countries; and European nations have some of the highest incidences. Poor prognosis and mortality rate is very often linked to formation of secondary tumour sites in these patients. In advanced stages of this cancer, cells strive to invade nearby tissues in a process called metastasis. More often than not, patients suffer more due to metastasis of cancer than through the original tumour. In this project, I will investigate the mechanisms which lead to bladder cancer metastasis; identify key components in the pathways and also test out specific inhibitors to mitigate the growth and/or metastasis. Having an acute knowledge of ‘how and which’ pathway(s) promote metastasis in bladder cancer should provide us with information so that specific components can be targeted. Moreover, the proposed study also focuses on developing state-of-the-art biomarker strategies to identify patient populations which will best benefit from our inhibitor therapies. This project will enable the translation of experimental results obtained from lab bench to understanding how some patients will best benefit from certain inhibitor therapies.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2017

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Coordinator

ACADEMISCH ZIEKENHUIS LEIDEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 177 598,80
Address
ALBINUSDREEF 2
2333 ZA Leiden
Netherlands

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Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 177 598,80
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