Membrane-based nano-mechanobiology: Role of mechanical forces in remodelling the spatiotemporal nanoarchitecture of the plasma membrane

Project Information

NANO-MEMEC

Grant agreement ID: 788546

DOI

10.3030/788546

Project closed

EC signature date 25 May 2018

Start date 1 December 2018

End date 31 May 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 212 063,00

EU contribution

€ 2 212 063,00

Coordinated by

FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (16)

Impact of Glycans on Lipid Membrane Dynamics at the Nanoscale Unveiled by Planar Plasmonic Nanogap Antennas and Atomic Force Spectroscopy

Author(s): Pamina M. Winkler, Felix Campelo, Marina I. Giannotti, Maria F. Garcia-Parajo
Published in: The Journal of Physical Chemistry Letters, Issue 12/4, 2021, Page(s) 1175-1181, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.0c03439

A physical mechanism of TANGO1-mediated bulky cargo export

Author(s): Ishier Raote, Morgan Chabanon, Nikhil Walani, Marino Arroyo, Maria F Garcia-Parajo, Vivek Malhotra, Felix Campelo
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.59426

Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration

Author(s): Izabela K. Piechocka, Sarah Keary, Alberto Sosa-Costa, Lukas Lau, Nitin Mohan, Jelena Stanisavljevic, Kyra J.E. Borgman, Melike Lakadamyali, Carlo Manzo, Maria F. Garcia-Parajo
Published in: Biophysical Journal, Issue 120/13, 2021, Page(s) 2644-2656, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2021.05.016

Early Steps of Individual Multireceptor Viral Interactions Dissected by High-Density, Multicolor Quantum Dot Mapping in Living Cells

Author(s): Nicolas Mateos, Enric Gutierrez-Martinez, Jessica Angulo-Capel, Irene Carlon-Andres, Sergi Padilla-Parra, Maria F. Garcia-Parajo, Juan A. Torreno-Pina
Published in: ACS Nano, Issue 18, 2024, Page(s) 28881-28893, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.4c09085

Tensing Flipper: Photosensitized Manipulation of Membrane Tension, Lipid Phase Separation, and Raft Protein Sorting in Biological Membranes

Author(s): Joaquim Torra, Felix Campelo, Maria F. Garcia-Parajo
Published in: Journal of the American Chemical Society, Issue 146, 2024, Page(s) 24114-24124, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c08580

Stochastic particle unbinding modulates growth dynamics and size of transcription factor condensates in living cells

Author(s): Gorka Muñoz-Gil, Catalina Romero-Aristizabal, Nicolas Mateos, Felix Campelo, Lara I. de Llobet Cucalon, Miguel Beato, Maciej Lewenstein, Maria F. Garcia-Parajo, Juan A. Torreno-Pina
Published in: PNAS, Issue 119, 2022, Page(s) e2200667119, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2200667119

Sorting of secretory proteins at the trans-Golgi network by human TGN46

Author(s): Pablo Lujan, Carla Garcia-Cabau, Yuichi Wakana, Javier Vera Lillo, Carmen Rodilla-Ramírez, Hideaki Sugiura, Vivek Malhotra, Xavier Salvatella, Maria F Garcia-Parajo, Felix Campelo
Published in: eLife, Issue 12, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.91708

Dynamic actin-mediated nano-scale clustering of CD44 regulates its meso-scale organization at the plasma membrane

Author(s): Parijat Sil, Nicolas Mateos, Sangeeta Nath, Sonja Buschow, Carlo Manzo, Kenichi G. N. Suzuki, Takahiro Fujiwara, Akihiro Kusumi, Maria F. Garcia-Parajo, Satyajit Mayor
Published in: Molecular Biology of the Cell, Issue 31/7, 2020, Page(s) 561-579, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1091/mbc.e18-11-0715

Nanoscale control of single molecule Förster resonance energy transfer by a scanning photonic nanoantenna

Author(s): Maria Sanz-Paz, Jerome Wenger, Niek F. van Hulst, Mathieu Mivelle, Maria F. Garcia-Parajo
Published in: Nanophotonics, Issue 0/0, 2020, ISSN 2192-8614
Publisher: Nanophotonics
DOI: 10.1515/nanoph-2020-0221

Actin-regulated Siglec-1 nanoclustering influences HIV-1 capture and virus-containing compartment formation in dendritic cells

Author(s): Enric Gutiérrez-Martínez, Susana Benet Garrabé, Nicolas Mateos, Itziar Erkizia, Jon Ander Nieto-Garai, Maier Lorizate, Kyra JE Borgman, Carlo Manzo, Felix Campelo, Nuria Izquierdo-Useros, Javier Martinez-Picado, Maria F Garcia-Parajo
Published in: eLife, Issue 12, 2023, Page(s) e78836, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.78836

Harnessing the Power of Plasmonics for <i>in Vitro</i> and <i>in Vivo</i> Biosensing

Author(s): Ediz Kaan Herkert, Maria F. Garcia-Parajo
Published in: ACS Photonics, Issue 12, 2025, Page(s) 1259-1275, ISSN 2330-4022
Publisher: American Chemical Society
DOI: 10.1021/acsphotonics.4c01657

Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients

Author(s): Eva M. García-Cuesta, José Miguel Rodríguez-Frade, Sofía R. Gardeta, Gianluca D’Agostino, Pablo Martínez, Blanca Soler Palacios, Graciela Cascio , Tobias Wolf, Nicolas Mateos, Rosa Ayala-Bueno, César A. Santiago, Pilar Lucas, Lucia Llorente, Luis M. Allende, Luis Ignacio González-Granado, Noa Martín-Cófreces, Pedro Roda-Navarro, Federica Sallusto, Francisco Sánchez-Madrid, María F. Ga
Published in: PNAS, Issue 119, 2022, Page(s) e2119483119, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2119483119

The ubiquitous nanocluster: A molecular scale organizing principle that governs cellular information flow

Author(s): Maria F. Garcia-Parajo, Satyajit Mayor
Published in: Current Opinion in Cell Biology, Issue 86, 2024, Page(s) 102285, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2023.102285

Hexagonal Plasmonic Arrays for High-Throughput Multicolor Single-Molecule Studies

Author(s): Ediz Kaan Herkert, Lukas Lau, Roger Pons Lanau, Maria F. Garcia-Parajo
Published in: ACS Applied Materials &amp; Interfaces, Issue 16, 2024, Page(s) 41271-41280, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.4c04744

Correlative nanophotonic approaches to enlighten the nanoscale dynamics of living cell membranes

Author(s): Winkler, Pamina M.; Garcia-Parajo, Maria F.
Published in: Biochemical Society Transactions, 2021, ISSN 0300-5127
Publisher: Portland Press, Ltd.
DOI: 10.1042/bst20210457

Broadband Plasmonic Nanoantennas for Multi-Color Nanoscale Dynamics in Living Cells

Author(s): Maria Sanz-Paz, Thomas S. van Zanten, Carlo Manzo, Mathieu Mivelle, Maria F. Garcia-Parajo
Published in: Small, 2023, Page(s) e2207977, ISSN 1613-6829
Publisher: Wiley-VCH Verlag
DOI: 10.1002/smll.202207977

Other (1)

Differential spatial regulation and activation of integrin nanoclusters inside focal adhesions

Author(s): Sarah Keary, Nicolas Mateos, Felix Campelo, Maria F. Garcia-Parajo
Published in: BioRxiv / eLife, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.12.16.571970