Objective
The aim of this ERC Proof of Concept Grant proposal is the construction, validation, and patenting of a nanoscale device that can accurately measure the binding and unbinding kinetics of target molecules. Accurate measurement of binding and unbinding kinetics of molecules is of great interest to both pharmaceutical companies and academic research groups, and is essential for the development of novel therapeutic compounds. Our proposed nanodevice is based on our knowledge about dynamic nanostructures gained during the course of the ERC starting grant “DNA ORIGAMI DEVICES” and the current ERC consolidator grant “DNA ORIGAMI MOTORS”, and offers a range of advantages compared to existing competing technologies, such as significantly lower initial and running costs, a label-free assay with fluorescent readout, no necessity of time-resolved sample preparation, a solution-based measurement, greater experimental throughput, and control over target molecule arrangements on a molecular scale. In the course of this project, we will build a demonstrator nanodevice, secure relevant intellectual property rights, validate and improve the nanodevice in close collaboration with prospective end-users, and determine promising commercialization approaches. The expected outcomes are a licensable patent, a provisional business model, a technology with TRL 4-6, and foundations for subsequent collaboration projects with customers, suppliers, and competitors.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- social sciences economics and business business and management business models
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2017-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
80333 Muenchen
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.