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Concepts of Graph Theory Applied to the Human Microbiome

Objective

"Incidents of cancer, respiratory, and circulatory disease are the highest causes of death among members of the European Union (EU). Elements of these diseases have been linked to the human microbiota, the complex ecosystem of microorganisms which live on and in the human body. Understanding the disruptions to the human microbiota which cause disease is important in furthering our knowledge of these diseases. Although advances in sequencing technology have allowed the exploration of ""who"" is present in these communities, we still do not have a proper understanding of ""what"" is present in terms of genetic elements (genomes, operons, genes, and single nucleotide polymorphisms (SNPs)) due to a lack of computaional tools. In GRAHAM, I propose to apply network analysis to the study of disruptions to the human microbiota in order to develop tools and answer questions related to human health and disease.
Under this research programme, I will model interactions between genetic elements in publicly available metagenomic datasets of the human microbiota using networks. My background in metagenomic sequencing technologies will be combined with the excellence of a research environment and supervisor rich in experience with applications of network analyses. Deliverables will include open-source software packages, and results of this research will be disseminated via publications, conferences, workshops, and public seminars."

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2017

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Coordinator

THE UNIVERSITY OF NOTTINGHAM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 195 454,80
Address
University Park
NG7 2RD Nottingham
United Kingdom

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Region
East Midlands (England) Derbyshire and Nottinghamshire Nottingham
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 195 454,80
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