Objective
Nucleic acid storage and stability is of primary importance as it finds uses in material science as nanomachines, biosensors and bioelectronics. The long-term stability and storage of DNA is a major challenge as hydrolytic reactions cause its denaturation when stored in an aqueous environment with conventional buffer solutions. Most of the devices employing nucleic acids require the nucleic acid molecule (generally DNA) to be adsorbed on the surface with a solvent in its immediate vicinity. The search for suitable solvents and electrolytes received a boost with the advent of ionic liquids (ILs). Nucleic acids have showcased enhanced chemical and structural stability in ILs compared to conventional buffer solutions. However, to employ ILs as electrolytes or solvents in biosensors and bioelectronics it is paramount to understand the effect of IL ions on the adsorption and dynamics of DNA molecules on surfaces. The objective can be achieved by employing a synergistic approach of microscopy, spectroscopy and theory. Time lapse scanning force microscopy (SFM) and Tip Enhanced Raman Spectroscopy (TERS) supported by computational studies will give a comprehensive idea in this regard. In essence, the central research objective of NAIL is to understand, the role of the various stabilizing interactions on Nucleic Acids imposed by the ions of Ionic Liquids on the adsorption and dynamics of the former on surfaces. Along with the research objectives, the ultimate goal of the project is to propel me, Sugosh Prabhu to a position of professional independence at the forefront of academic/industrial research by enhancing my innovative potential, diversify my individual competences; and also to open up new avenues in terms of collaboration for me and the host organization.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences biological sciences biochemistry biomolecules nucleic acids
- natural sciences biological sciences genetics DNA
- natural sciences physical sciences optics microscopy
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2017
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3000 LEUVEN
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.