Bringing a prophylactic Ebola vaccine to licensure

Project Information

EBOVAC3

Grant agreement ID: 800176

DOI 10.3030/800176

Project closed

EC signature date 15 June 2018

Start date 1 June 2018

End date 30 September 2024

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 50 979 889,71

EU contribution € 29 402 655,71

Coordinated by

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom

Objective

The overall aim of EBOVAC3 is to support an essential part of remaining clinical and manufacturing activities required for licensure in the European Union (EU) and the United States (US) of a candidate heterologous prime-boost prophylactic vaccine regimen against Ebola virus disease that is under development at Janssen Vaccines & Prevention B.V. The intended target indication is defined as:

“A prime-boost regimen with Ad26.ZEBOV as prime vaccine and MVA-BN®-Filo as boost vaccine indicated for the prevention of Ebola virus disease (EVD) caused by EBOV of the Zaire ebolavirus species in adults and elderly (aged ≥65 years), human immunodeficiency virus (HIV)-infected adults, and children aged ≥1 year.”

Fields of science

• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › health sciences › infectious diseases › RNA viruses › ebola
• medical and health sciences › health sciences › infectious diseases › RNA viruses › HIV
• medical and health sciences › basic medicine › pharmacology and pharmacy › pharmaceutical drugs › vaccines

Keywords

• Ebola

Programme(s)

• H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme
• H2020-EU.3.1.7. - Innovative Medicines Initiative 2 (IMI2)

Topic(s)

• IMI2-2015-08-01 - Ebola and other filoviral haemorrhagic fevers (Ebola+) programme: future outbreaks

Call for proposal

H2020-JTI-IMI2-2015-08-single-stage

Funding Scheme

RIA - Research and Innovation action

Coordinator

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER

• Net EU contribution: € 12 162 503,75
• Address: KEPPEL STREET ; WC1E 7HT London ; United Kingdom
• Region: London › Inner London — West › Camden and City of London
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 12 162 503,75

Participants (9)

JANSSEN VACCINES & PREVENTION BV

Netherlands

• Net EU contribution: € 0,00
• Address: ARCHIMEDESWEG 4 ; 2333 CN Leiden
• Region: West-Nederland › Zuid-Holland › Agglomeratie Leiden en Bollenstreek
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Total cost: € 21 420 940,00

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

• Net EU contribution: € 3 094 686,62
• Address: RUE DE TOLBIAC 101 ; 75654 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Total cost: € 3 515 103,12

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITE DE BORDEAUX

France

• Net EU contribution: € 200 030,25
• Address: PLACE PEY BERLAND 35 ; 33000 Bordeaux
• Region: Nouvelle-Aquitaine › Aquitaine › Gironde
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CHU HOPITAUX DE BORDEAUX

France

• Net EU contribution: € 217 886,25
• Address: RUE DUBERNAT 12 ; 33404 Talence
• Region: Nouvelle-Aquitaine › Aquitaine › Gironde
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITE PARIS CITE

France

• Net EU contribution: € 2 500,00
• Address: 85 BD SAINT GERMAIN ; 75006 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data

UNIVERSITEIT ANTWERPEN

Belgium

• Net EU contribution: € 5 532 935,34
• Address: PRINSSTRAAT 13 ; 2000 Antwerpen
• Region: Vlaams Gewest › Prov. Antwerpen › Arr. Antwerpen
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 5 532 935,34

UNIVERSITY OF SIERRA LEONE

Sierra Leone

• Net EU contribution: € 4 898 982,15
• Address: COLLEGE OF MEDECINE & ALLIED HEALTH SCIENCES UNIVERSITY OF SIERRA LEONE NEW ENGLAND ; Freetown
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 4 898 982,15

COALITION FOR EPIDEMIC PREPAREDNESS INNOVATIONS

Norway

• Net EU contribution: € 0,00
• Address: SKOYEN ATRIUM ASKEKROKEN 11 ; 0277 OSLO
• Region: Norge › Oslo og Viken › Oslo
• Activity type: Research Organisations
• Total cost: € 156 294,00

UNIVERSITE DE KINSHASA

Democratic Republic of the Congo

• Net EU contribution: € 3 293 131,35
• Address: Campus Universitaire de Kinshasa ; N/A KINSHASA
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 3 293 131,35