Defining the intrinsic transcriptional programs and the microenvironmental signals tailoring lung Interstitial Macrophage IDentity

Project Information

IM-ID

Grant agreement ID: 801823

DOI

10.3030/801823

Project closed

EC signature date 22 October 2018

Start date 1 January 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

UNIVERSITE DE LIEGE
Belgium

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation

Author(s): Domien Vanneste, Qiang Bai, Shakir Hasan, Wen Peng, Dimitri Pirottin, Joey Schyns, Pauline Maréchal, Cecilia Ruscitti, Margot Meunier, Zhaoyuan Liu, Céline Legrand, Laurence Fievez, Florent Ginhoux, Coraline Radermecker, Fabrice Bureau and Thomas Marichal
Published in: Nature Immunology, Issue 24(5), 2023, Page(s) 827-840, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-023-01468-3

Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3⁺ Regulatory T Cells

Author(s): Céline Legrand, Domien Vanneste, Alexandre Hego, Catherine Sabatel, Kiréna Mollers, Joey Schyns, Pauline Maréchal, Joan Abinet, Amandine Tytgat, Maude Liégeois, Barbara Polese, Margot Meunier, Coraline Radermecker, Laurence Fiévez, Fabrice Bureau, Thomas Marichal
Published in: American Journal of Respiratory Cell and Molecular Biology, Issue 70, 2024, Page(s) 446-456, ISSN 1044-1549
Publisher: American Lung Association
DOI: 10.1165/rcmb.2023-0254oc

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

Author(s): Svetoslav Chakarov, Hwee Ying Lim, Leonard Tan, Sheau Yng Lim, Peter See, Josephine Lum, Xiao-Meng Zhang, Shihui Foo, Satoshi Nakamizo, Kaibo Duan, Wan Ting Kong, Rebecca Gentek, Akhila Balachander, Daniel Carbajo, Camille Bleriot, Benoit Malleret, John Kit Chung Tam, Sonia Baig, Muhammad Shabeer, Sue-Anne Ee Shiow Toh, Andreas Schlitzer, Anis Larbi, Thomas Marichal, Bernard Malissen, Jinmiao Chen
Published in: Science, Issue 363/6432, 2019, Page(s) eaau0964, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aau0964

Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Author(s): Joey Schyns, Qiang Bai, Cecilia Ruscitti, Coraline Radermecker, Sebastiaan De Schepper, Svetoslav Chakarov, Frédéric Farnir, Dimitri Pirottin, Florent Ginhoux, Guy Boeckxstaens, Fabrice Bureau, Thomas Marichal
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-11843-0

Non-peer reviewed articles (2)

Endothelial cells instruct macrophages on how to Rspond to lung injury

Author(s): Thomas Marichal
Published in: Nature Immunology, Issue 21/11, 2020, Page(s) 1317-1318, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-020-00806-z

Monocytes can proliferate in vacant niches before differentiation into macrophages

Author(s): Domien Vanneste, Thomas Marichal
Published in: Nature Immunology, Issue 24, 2023, Page(s) 749-750, ISSN 1529-2908
Publisher: Nature Publishing Group