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Epigenetic fine-tuning of T cells for improved adoptive cell therapy


Targeted De-Methylation of the FOXP3-TSDR Is Sufficient to Induce Physiological FOXP3 Expression but Not a Functional Treg Phenotype

Author(s): Christopher Kressler, Gilles Gasparoni, Karl Nordström, Dania Hamo, Abdulrahman Salhab, Christoforos Dimitropoulos, Sascha Tierling, Petra Reinke, Hans-Dieter Volk, Jörn Walter, Alf Hamann, Julia K. Polansky
Published in: Frontiers in Immunology, Issue 11, 2021, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2020.609891

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