CORDIS - EU research results

Challenges on the road to genome duplication: Single-molecule approaches to study replisome collisions



The fork protection complex recruits FACT to reorganize nucleosomes during replication

Author(s): Safaric, B., Chacin, E., Scherr, M. J., Rajappa, L., Gebhardt, C., Kurat, C., Cordes, Th., 3Duderstadt, K. E.
Published in: Nucleic Acids Research, Issue gkac005, 2022, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac005

Mars, a molecule archive suite for reproducible analysis and reporting of single molecule properties from bioimages.

Author(s): Nadia M Huisjes; Thomas M Retzer; Matthias J Scherr; Rohit Agarwal; Lional Rajappa; Barbara Safaric; Anita Minnen; Karl E Duderstadt.
Published in: eLife, Issue 11, 2022, Page(s) e75899, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.75899

Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision

Author(s): Rohit Agarwal, Karl E. Duderstadt
Published in: Nature Communications, Issue 11/1, 2020, Page(s) 4714, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-18456-y

Human NLRP1 is a sensor for double-stranded RNA

Author(s): Stefan Bauernfried, Matthias J. Scherr, Andreas Pichlmair, Karl E. Duderstadt, Veit Hornung
Published in: Science, Issue 371/6528, 2021, Page(s) eabd0811, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abd0811

MCM complexes are barriers that restrict cohesin-mediated loop extrusion.

Author(s): Dequeker BJH, Scherr MJ, Brandão HB, Gassler J, Powell S, Gaspar I, Flyamer IM, Lalic A, Tang W, Stocsits R, Davidson IF, Peters JM, Duderstadt KE, Mirny LA, Tachibana K.
Published in: Nature, Issue 606/7912, 2022, Page(s) 197-203, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04730-0

Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase.

Author(s): Scherr MJ, Wahab SA, Remus D, Duderstadt KE.
Published in: Cell Reports, Issue 38/12, 2022, Page(s) 110531, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.110531

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