Gaining insights into human evolution and disease prevention from adaptive natural selection driven by lethal epidemics

Project Information

SELECTIONDRIVEN

Grant agreement ID: 804679

DOI

10.3030/804679

Project closed

EC signature date 7 November 2018

Start date 1 January 2019

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 600,00

EU contribution

€ 1 499 600,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

LocalNgsRelate: a software tool for inferring IBD sharing along the genome between pairs of individuals from low-depth NGS data

Author(s): Alissa L Severson, Thorfinn Sand Korneliussen, Ida Moltke
Published in: Bioinformatics, Issue Volume 38, Issue 4, 15 February 2022, 2022, Page(s) 1159–1161, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btab732

SimOutbreakSelection: a simulation-based tool to optimise sampling design and analysis strategies for detecting epidemic-driven selection

Author(s): Cindy G. Santander, Ida Moltke
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-61574-8

Colonialism in South Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo

Author(s): Liam Quinn, Genís Garcia-Erill, Cindy Santander, Anna Brüniche-Olsen, Xiaodong Liu, Mikkel-Holger S. Sinding, Michael P. Heaton, Timothy P. L. Smith, Patrícia Pečnerová, Laura D. Bertola, Kristian Hanghøj, Malthe Sebro Rasmussen, Deon de Jager, Hans R. Siegismund, Anders Albrechtsen, Rasmus Heller, Ida Moltke
Published in: Molecular Ecology, Issue 32, 2023, Page(s) 1860-1874, ISSN 1365-294X
Publisher: Wiley
DOI: 10.1111/mec.16851

NGSremix: a software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data

Author(s): Anne Krogh Nøhr, Kristian Hanghøj, Genís Garcia-Erill, Zilong Li, Ida Moltke, Anders Albrechtsen
Published in: G3, Issue Volume 11, 2021, ISSN 2160-1836
Publisher: Genetics Society of America
DOI: 10.1093/g3journal/jkab174

Insufficient evidence for natural selection associated with the Black Death

Author(s): Alison R. Barton, Cindy G. Santander, Pontus Skoglund, Ida Moltke, David Reich, Iain Mathieson
Published in: Nature, Issue 638, 2025, Page(s) E19-E22, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1101/2023.03.14.532615

Population Structure and Migration in the Eastern Highlands of Papua New Guinea; a Region Impacted by the kuru Epidemic

Author(s): Liam Quinn, Ida Moltke, Jerome Whitfield, Michael Alpers, Tracy Campbell, Holger Hummerich, William Pomat, Peter Siba, George Koki, John Collinge, Garrett Hellenthal, Simon Mead
Published in: American Journal of Human Genetics, Issue 111, 2025, Page(s) 668-679, ISSN 0002-9297
Publisher: University of Chicago Press
DOI: 10.1101/2022.09.26.509478