Spontaneous and sensory-evoked activity shape neural circuits in the developing brain

Project Information

NeuroDevo

Grant agreement ID: 804824

DOI

10.3030/804824

Project closed

EC signature date 17 October 2018

Start date 1 September 2019

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 290 525,00

EU contribution

€ 1 290 525,00

Coordinated by

TECHNISCHE UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Other (4)

Cell-type-specific synaptic scaling mechanisms differentially contribute to associative learning

Author(s): Fabio Veneto, Ayça Kepçe, Yue Kris Wu, Julijana Gjorgjieva
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.05.14.654005

Structured stabilization in recurrent neural circuits through inhibitory synaptic plasticity

Author(s): Dylan Festa, Claudia Cusseddu, Julijana Gjorgjieva
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.12.618014

Assembly-based computations through contextual dendritic gating of plasticity

Author(s): Sebastian Onasch, Christoph Miehl, M. Maurycy Miękus, Julijana Gjorgjieva
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.07.22.666089

Spontaneous emergence and evolution of neuronal sequences in recurrent networks

Author(s): Shuai Shao, Juan Luis Riquelme, Julijana Gjorgjieva
Published in: 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.09.27.615499

Peer reviewed articles (16)

Oxytocin Shapes Spontaneous Activity Patterns in the Developing Visual Cortex by Activating Somatostatin Interneurons

Author(s): Paloma P. Maldonado, Alvaro Nuno-Perez, Jan H. Kirchner, Elizabeth Hammock, Julijana Gjorgjieva, Christian Lohmann
Published in: Current Biology, Issue 31/2, 2021, Page(s) 322-333.e5, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2020.10.028

Regulation of circuit organization and function through inhibitory synaptic plasticity

Author(s): Yue Kris Wu, Christoph Miehl, Julijana Gjorgjieva
Published in: Trends in Neurosciences, Issue 45, 2025, Page(s) 884-898, ISSN 0166-2236
Publisher: Elsevier BV
DOI: 10.1016/j.tins.2022.10.006

Modeling the Emergence of Circuit Organization and Function during Development

Author(s): Shreya Lakhera, Elizabeth Herbert, Julijana Gjorgjieva
Published in: Cold Spring Harbor Perspectives in Biology, Issue 17, 2025, Page(s) a041511, ISSN 1943-0264
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a041511

Emergence of synaptic organization and computation in dendrites

Author(s): Jan H. Kirchner, J. Gjorgjieva
Published in: Neuroforum, 2022, ISSN 2363-7013
Publisher: De Gruyter
DOI: 10.1515/nf-2021-0031

Homeostatic mechanisms regulate distinct aspects of cortical circuit dynamics

Author(s): Yue Kris Wu, Keith B. Hengen, Gina G. Turrigiano, Julijana Gjorgjieva
Published in: Proceedings of the National Academy of Sciences, Issue 117/39, 2020, Page(s) 24514-24525, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1918368117

Emergence of local and global synaptic organization on cortical dendrites

Author(s): Jan H. Kirchner, J. Gjorgjieva
Published in: Nat Commun, Issue 12(1):4005, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23557-3

Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity

Author(s): Jan H Kirchner, Lucas Euler, Ingo Fritz, André Ferreira Castro, Julijana Gjorgjieva
Published in: eLife, Issue 12, 2025, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.87527.3

Adaptation of spontaneous activity in the developing visual cortex

Author(s): Marina E Wosniack, Jan H Kirchner, Ling-Ya Chao, Nawal Zabouri, Christian Lohmann, Julijana Gjorgjieva
Published in: eLife, Issue 10, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.61619

Pre-training artificial neural networks with spontaneous retinal activity improves motion prediction in natural scenes

Author(s): Lilly May, Alice Dauphin, Julijana Gjorgjieva
Published in: PLOS Computational Biology, Issue 21(3): e1012830, 2025, ISSN 1553-734X
Publisher: Public Library of Science
DOI: 10.1101/2024.06.15.599143

Inhibition stabilization and paradoxical effects in recurrent neural networks with short-term plasticity

Author(s): Yue Kris Wu, Julijana Gjorgjieva
Published in: Physical Review REsearch, Issue 5, 2024, Page(s) 033023, ISSN 2643-1564
Publisher: Physical Review Research is the American Physical Society (APS)
DOI: 10.1101/2022.12.19.520986

Top-down modulation in canonical cortical circuits with short-term plasticity

Author(s): Felix Waitzmann, Yue Kris Wu, Julijana Gjorgjieva
Published in: Proceedings of the National Academy of Sciences USA, Issue 121(16), 2024, Page(s) e2311040121, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1101/2023.06.13.544791

Sensory experience steers representational drift in mouse visual cortex

Author(s): Joel Bauer, Uwe Lewin, Elizabeth Herbert, Julijana Gjorgjieva, Carl E. Schoonover, Andrew J. P. Fink, Tobias Rose, Tobias Bonhoeffer, Mark Hübener
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-53326-x

Autonomous emergence of connectivity assemblies via spike triplet interactions

Author(s): Lisandro Montangie, Christoph Miehl, Julijana Gjorgjieva
Published in: PLOS Computational Biology, Issue 16/5, 2020, Page(s) e1007835, ISSN 1553-7358
Publisher: PLOS Computational Biology
DOI: 10.1371/journal.pcbi.1007835

Synapse-type-specific competitive Hebbian learning forms functional recurrent networks

Author(s): Samuel Eckmann, Edward James Young, Julijana Gjorgjieva
Published in: Proceedings of the National Academy of Sciences, Issue 121, 2024, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2305326121

Formation and computational implications of assemblies in neural circuits

Author(s): Christoph Miehl, Sebastian Onasch, Dylan Festa, Julijana Gjorgjieva
Published in: The Journal of Physiology, Issue 601, 2023, Page(s) 3071-3090, ISSN 0022-3751
Publisher: Blackwell Publishing Inc.
DOI: 10.1113/jp282750

A circuit mechanism for independent modulation of excitatory and inhibitory firing rates after sensory deprivation

Author(s): Leonidas M. A. Richter, Julijana Gjorgjieva
Published in: Proceedings of the National Academy of Sciences, Issue 119, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2116895119

Non-peer reviewed articles (1)

FENS‐Kavli Network of Excellence: Mentorship during the COVID‐19 pandemic: Perspectives, challenges and opportunities

Author(s): Sapir Sela‐Vasiliu, Christoph Miehl, Hanne Huygelier, Meital Oren‐Suissa, Julijana Gjorgjieva, Celine R. Gillebert
Published in: European Journal of Neuroscience, Issue 58, 2024, Page(s) 4429-4437, ISSN 0953-816X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ejn.15797