Molecular Signaling in Health and Disease - Interdisciplinary Centre of Excellence

Deliverables

Documents, reports (1)

OA policy

Websites, patent fillings, videos etc. (1)

Links to MOSaIC, the new laboratory, and social media websites

Links to MOSaIC the new laboratory and social media websites

Publications

Peer reviewed articles (17)

Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings

Author(s): Anna Hojka-Osinska; Aleksander Chlebowski; Joanna Grochowska; Ewelina P. Owczarek; Kamila Affek; Kamila Kłosowska-Kosicka; Roman J. Szczesny; Andrzej Dziembowski
Published in: iScience, Vol 24, Iss 9, Pp 103036- (2021), 2, 2021, ISSN 2589-0042
Publisher: ScienceDirect
DOI: 10.1016/j.isci.2021.103036

Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C

Author(s): Bilska A, Kusio-Kobiałka M, Krawczyk PS, Gewartowska O, Tarkowski B, Kobyłecki K, Nowis D, Golab J, Gruchota J, Borsuk E, Dziembowski A, Mroczek S.
Published in: Nature Communications, 11, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-15835-3

Three-layered control of mRNA poly(A) tail synthesis in <i>Saccharomyces cerevisiae</i>

Author(s): Matti Turtola; M. Cemre Manav; Ananthanarayanan Kumar; Agnieszka Tudek; Seweryn Mroczek; Paweł S. Krawczyk; Andrzej Dziembowski; Manfred Schmid; Lori A. Passmore; Ana Casañal; Torben Heick Jensen
Published in: Genes & Development, 2, 2021, ISSN 1549-5477
Publisher: Cold Spring Harbor Laboratory Press in association with The Genetics Society
DOI: 10.1101/gad.348634.121

Functions and mechanisms of RNA tailing by metazoan terminal nucleotidyltransferases

Author(s): Vladyslava Liudkovska, Andrzej Dziembowski
Published in: Wiley Interdisciplinary Reviews: RNA, 12(2), 2020, ISSN 1757-7004
Publisher: John Wiley and Sons Inc.
DOI: 10.1002/wrna.1622

SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments

Author(s): Paweł Piątkowski, Jagoda Jabłońska, Adriana Żyła, Dorota Niedziałek, Dorota Matelska, Elżbieta Jankowska, Tomasz Waleń, Wayne K. Dawson, Janusz M. Bujnicki
Published in: Nucleic Acids Research, 45/16, 2017, Page(s) e150-e150, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx631

Retro-translocation of mitochondrial intermembrane space proteins

Author(s): Piotr Bragoszewski, Michal Wasilewski, Paulina Sakowska, Agnieszka Gornicka, Lena Böttinger, Jian Qiu, Nils Wiedemann, Agnieszka Chacinska
Published in: Proceedings of the National Academy of Sciences, 112/25, 2015, Page(s) 7713-7718, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1504615112

On the role of steric clashes in methylation control of restriction endonuclease activity

Author(s): Karolina Mierzejewska, Matthias Bochtler, Honorata Czapinska
Published in: Nucleic Acids Research, 44/1, 2016, Page(s) 485-495, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkv1341

Redundans: an assembly pipeline for highly heterozygous genomes

Author(s): Leszek P. Pryszcz, Toni Gabaldón
Published in: Nucleic Acids Research, 44/12, 2016, Page(s) e113-e113, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkw294

SimRNAweb: a web server for RNA 3D structure modeling with optional restraints

Author(s): Marcin Magnus, Michał J. Boniecki, Wayne Dawson, Janusz M. Bujnicki
Published in: Nucleic Acids Research, 44/W1, 2016, Page(s) W315-W319, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkw279

Coordination between the polymerase and RNase H activity of HIV-1 reverse transcriptase

Author(s): Małgorzata Figiel, Miroslav Krepl, Jarosław Poznański, Agnieszka Gołąb, Jiří Šponer, Marcin Nowotny
Published in: Nucleic Acids Research, 2017, Page(s) gkx004, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx004

Modeling of ribonucleic acid-ligand interactions

Author(s): Filip Stefaniak, Ewa I. Chudyk, Michael Bodkin, Wayne K. Dawson, Janusz M. Bujnicki
Published in: Wiley Interdisciplinary Reviews: Computational Molecular Science, 5/6, 2015, Page(s) 425-439, ISSN 1759-0876
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/wcms.1226

Chatty Mitochondria: Keeping Balance in Cellular Protein Homeostasis

Author(s): Ulrike Topf, Lidia Wrobel, Agnieszka Chacinska
Published in: Trends in Cell Biology, 26/8, 2016, Page(s) 577-586, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2016.03.002

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

Author(s): Lidia Wrobel, Ulrike Topf, Piotr Bragoszewski, Sebastian Wiese, Malgorzata E. Sztolsztener, Silke Oeljeklaus, Aksana Varabyova, Maciej Lirski, Piotr Chroscicki, Seweryn Mroczek, Elzbieta Januszewicz, Andrzej Dziembowski, Marta Koblowska, Bettina Warscheid, Agnieszka Chacinska
Published in: Nature, 524/7566, 2015, Page(s) 485-488, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature14951

NPDock: a web server for protein–nucleic acid docking

Author(s): Irina Tuszynska, Marcin Magnus, Katarzyna Jonak, Wayne Dawson, Janusz M. Bujnicki
Published in: Nucleic Acids Research, 43/W1, 2015, Page(s) W425-W430, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkv493

Sequence-specific cleavage of dsRNA by Mini-III RNase

Author(s): Dawid Głów, Dariusz Pianka, Agata A. Sulej, Łukasz P. Kozłowski, Justyna Czarnecka, Grzegorz Chojnowski, Krzysztof J. Skowronek, Janusz M. Bujnicki
Published in: Nucleic Acids Research, 43/5, 2015, Page(s) 2864-2873, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkv009

A long noncoding RNA promotes parasite differentiation in African trypanosomes.

Author(s): Fabien Guegan; K. Shanmugha Rajan; Fábio Bento; Daniel Pinto-Neves; Mariana Sequeira; Natalia Gumińska; Seweryn Mroczek; Andrzej Dziembowski; Smadar Cohen-Chalamish; Tirza Doniger; Beathrice Galili; Antonio M. Estévez; Cedric Notredame; Shulamit Michaeli; Luisa M. Figueiredo
Published in: Crossref, VOL. 8, NO. 24, 2022, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn2706

Global view on the metabolism of RNA poly(A) tails in yeast Saccharomyces cerevisiae

Author(s): Agnieszka Tudek; Katarzyna Matylla-Kulińska; Pawel S Krawczyk; Torben Heick Jensen; Andrzej Dziembowski; Rafal Tomecki; Matti Turtola; Seweryn Mroczek
Published in: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021), 1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25251-w