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Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics.

Deliverables

RNAct website and social media networks online

The RNAct website and social media channels are set up and working.

Supervisory board

The Management and Supervisory board members, as well as subcommittee managers, are officially appointed and installed, with the first supervisory board meeting taken place. The supervisory board will consist of the following members: The network coordinator and the deputy coordinator: - Wim Vranken (network coordinator, VUB) - Michael Sattler (deputy coordinator, HMGU) The beneficiaries: - Isaure Chauvot de Beauchene (CNRS) - Guillermo Rodrigo (CSIC) - Karl Andersson (RV) - Tommaso Martelli (GIO) - Ulrich Rant (DBS) The partners: - André Matagne (ULg) - Malika Smail-Tabbone (UL) - Helena Danielson (UU) - Marco Fragai (UF) - Camelo Lópeza (UPV) - Martin Zacharias (TUM) - The to-be-appointed program manager - One of the RNAct ESRs (to be selected by their ESR peers) - Up to 3 external members (to be appointed)

Advertising of all ESR positions

All ESR positions will be advertised by the start of the project

Tool for interpretation of RRMs in biophysical space

An integrated software tool will be created and made available that will link the sequence-based 'biophysical space' predictions from the Vranken group to RRM behaviour, such as RNA binding.

Publications

b2bTools: online predictions for protein biophysical features and their conservation

Author(s): Luciano Porto Kagami, Gabriele Orlando, Daniele Raimondi, Francois Ancien, Bhawna Dixit, Jose Gavaldá-García, Pathmanaban Ramasamy, Joel Roca-Martínez, Konstantina Tzavella, Wim Vranken
Published in: Nucleic Acids Research, 31 May 2021, 2021, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab425

Online biophysical predictions for SARS-CoV-2 proteins

Author(s): Luciano Kagami, Joel Roca-Martínez, Jose Gavaldá-García, Pathmanaban Ramasamy, K. Anton Feenstra, Wim F. Vranken
Published in: BMC Molecular and Cell Biology, 22/1, 2021, ISSN 2661-8850
Publisher: BioMed Central Ltd.
DOI: 10.1186/s12860-021-00362-w

Software

Tool for interpretation of RRMs in biophysical space

Author(s): Roca-Martínez, Joel; Vranken, Wim
DOI: 10.5281/zenodo.4655852; 10.5281/zenodo.4655851
Publisher: Zenodo