Project description DEENESFRITPL A tiny minnow draws a crowd Scientists are always in search of model systems that can help them study in the simplest, fastest and most effective ways disease pathways that affect humans. A tiny fish in the minnow family has proven extremely valuable in this regard. The zebrafish shares 70 % of the genes found in humans and many critical signalling pathways. The eggs are fertilised externally, facilitating developmental interventions and studies, and the resulting embryos are transparent, meaning development can be watched under a microscope. The EU-funded ZENITH project is preparing a new generation of scientists for interdisciplinary collaboration on pressing neuroscience challenges utilising the zebrafish model system and leveraging academic and industrial mentoring. The team will emerge with skills in visualisation, gene editing and computational modelling to study the nervous system and enhance understanding from cells to circuits to behaviour. Show the project objective Hide the project objective Objective A fundamental challenge for Neuroscience is to understand how neural circuits process information from the outside world and internal physiological states, to produce versatile but reliable behavior. Two major research challenges are: 1) the complexity and distributed nature of neural circuits; 2) the need for data spanning multiple scales from molecular and activity phenotypes of single cells through to circuit connectivity and population dynamics and finally the behavioral output itself. The goal of the ZENITH ETN, “ZEbrafish Neuroscience Interdisciplinary Training Hub”, is to understand how neural networks mediate perception and behavior. We will exploit the advantages of zebrafish as a small transparent vertebrate with superb genetic accessibility and use cutting-edge technology to elucidate the interactions between molecules, cells and entire networks that ultimately generate adaptive behavior. Our training goal is to create collaborative, interdisciplinary young scientists who can tackle major challenges within neuroscience research. Training in cutting-edge technologies and analytical frameworks will enable this next generation of researchers to perform integrated, multi-scale analyses to elucidate the neural basis of naturalistic behavior. Training is centered on highly collaborative projects between physicists, mathematicians and biologists that will expose ESRs to broad training with academic and industrial partners. Advanced optical methods and genome-editing will be utilized to link molecules to circuits, to map connectivity between cell types across the nervous system and to build computational models of brain activity that will be experimentally tested. Overall ZENITH will help to change the way young scientists are trained in Europe and provide the conceptual, technical and analytical skills needed to take on the challenge of understanding how the beautifully complex circuits of the vertebrate brain control behavior. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencescomputer and information sciencesartificial intelligencecomputational intelligence Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2018 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2018 See other projects for this call Funding Scheme MSCA-ITN-ETN - European Training Networks Coordinator INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE Net EU contribution € 549 604,08 Address Boulevard de l'hopital 47 75013 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (10) Sort alphabetically Sort by Net EU contribution Expand all Collapse all SORBONNE UNIVERSITE France Net EU contribution € 824 406,12 Address 21 rue de l'ecole de medecine 75006 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY COLLEGE LONDON United Kingdom Net EU contribution € 909 517,68 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THE UNIVERSITY OF EDINBURGH United Kingdom Net EU contribution € 303 172,56 Address Old college, south bridge EH8 9YL Edinburgh See on map Region Scotland Eastern Scotland Edinburgh Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Participation ended Germany Net EU contribution € 0,00 Address Hofgartenstrasse 8 80539 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CHARITE - UNIVERSITAETSMEDIZIN BERLIN Germany Net EU contribution € 252 788,40 Address Chariteplatz 1 10117 Berlin See on map Region Berlin Berlin Berlin Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD Portugal Net EU contribution € 237 720,24 Address Avenida brasilia, centro de investigacao da fundacao champalimaud 1400-038 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACIO CENTRE DE REGULACIO GENOMICA Spain Net EU contribution € 250 904,88 Address Carrer doctor aiguader 88 08003 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ZECLINICS SL Spain Net EU contribution € 250 904,88 Address Ctra de can ruti, cami de les escoles, s/n laboratori p0-8, edifici igtp muntanya 08916 Barcelona See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Este Cataluña Barcelona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT WIEN Austria Net EU contribution € 264 207,24 Address Universitatsring 1 1010 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TECHNISCHE UNIVERSITAET MUENCHEN Germany Net EU contribution € 252 788,40 Address Arcisstrasse 21 80333 Muenchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (11) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSIDADE NOVA DE LISBOA Portugal Net EU contribution € 0,00 Address Campus de campolide 1099 085 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSIDAD POMPEU FABRA Spain Net EU contribution € 0,00 Address Placa de la merce, 10-12 08002 Barcelona See on map Region Este Cataluña Barcelona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. PRESIDENT AND FELLOWS OF HARVARD COLLEGE United States Net EU contribution € 0,00 Address Massachusetts avenue 1350 02138 Cambridge See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. SPRINGER NATURE LIMITED United Kingdom Net EU contribution € 0,00 Address 4 crinan street RG21 6XS Basingstoke hants See on map Region South East (England) Hampshire and Isle of Wight North Hampshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. Intelligent Imaging Innovations GmbH Germany Net EU contribution € 0,00 Address Königsallee 9-21 D-37081 Göttingen See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Niedersachsen Braunschweig Göttingen Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. PHASEVIEW France Net EU contribution € 0,00 Address Impasse de la noisette 2 91370 Verrieres le buisson See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Essonne Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. OSHA LIANG France Net EU contribution € 0,00 Address 2 rue de la paix 75002 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. UNIVERSITY OF UTAH United States Net EU contribution € 0,00 Address E federal way 1471 84102 Salt lake city utah See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. LAVISION BIOTEC GMBH Germany Net EU contribution € 0,00 Address Astastrasse 14 33617 Bielefeld See on map Region Nordrhein-Westfalen Detmold Bielefeld, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. INSTITUT DE RECHERCHES SERVIER France Net EU contribution € 0,00 Address 3 rue de la republique 92150 Suresnes See on map Region Ile-de-France Ile-de-France Hauts-de-Seine Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. IMAGINE OPTIC France Net EU contribution € 0,00 Address 18 rue charles de gaulle 91400 Orsay See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Essonne Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00