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Training network in drug discovery targeting TRIM Ubiquitin ligases in disease

Deliverables

Advertise positions for recruitment

Advertisement of the open call for PhD student positions available within the TRIM-NET network.

TRIM-NET website

Creation of the TRIM-NET website together with B9 (WP3)

Publications

MuRF1/TRIM63, Master Regulator of Muscle Mass

Author(s): Dulce Peris-Moreno, Daniel Taillandier, Cécile Polge
Published in: International Journal of Molecular Sciences, Issue 21/18, 2020, Page(s) 6663, ISSN 1422-0067
DOI: 10.3390/ijms21186663

TRIMming Down Hormone-Driven Cancers: The Biological Impact of TRIM Proteins on Tumor Development, Progression and Prognostication

Author(s): Eleonora Pauletto; Nils Eickhoff; Nuno Padrão; Christine Blattner; Wilbert Zwart
Published in: Cells, Vol 10, Iss 1517, p 1517 (2021), Issue 2, 2021, ISSN 2073-4409
DOI: 10.5445/ir/1000135752

To Ubiquitinate or Not to Ubiquitinate: TRIM17 in Cell Life and Death

Author(s): Meenakshi Basu-Shrivastava, Alina Kozoriz, Solange Desagher, Iréna Lassot
Published in: Cells, Issue 10/5, 2021, Page(s) 1235, ISSN 2073-4409
DOI: 10.3390/cells10051235

Rise of TRIM8: A Molecule of Duality

Author(s): Utsa Bhaduri, Giuseppe Merla
Published in: Molecular Therapy - Nucleic Acids, Issue 22, 2020, Page(s) 434-444, ISSN 2162-2531
DOI: 10.1016/j.omtn.2020.08.034

Targeting TRIM Proteins: A Quest towards Drugging an Emerging Protein Class

Author(s): Francesca D'Amico, Rishov Mukhopadhyay, Huib Ovaa, Monique P. C. Mulder
Published in: ChemBioChem, Issue 22/12, 2021, Page(s) 2011-2031, ISSN 1439-4227
DOI: 10.1002/cbic.202000787

TRIM32 and Malin in Neurological and Neuromuscular Rare Diseases

Author(s): Lorena Kumarasinghe, Lu Xiong, Maria Adelaida Garcia-Gimeno, Elisa Lazzari, Pascual Sanz, Germana Meroni
Published in: Cells, Issue 10/4, 2021, Page(s) 820, ISSN 2073-4409
DOI: 10.3390/cells10040820

Ubiquitin Ligases at the Heart of Skeletal Muscle Atrophy Control

Author(s): Dulce Peris-Moreno, Laura Cussonneau, Lydie Combaret, Cécile Polge, Daniel Taillandier
Published in: Molecules, Issue 26/2, 2021, Page(s) 407, ISSN 1420-3049
DOI: 10.3390/molecules26020407

Regulation of p53 by E3s

Author(s): Mengwu Pan, Christine Blattner
Published in: Cancers, Issue 13/4, 2021, Page(s) 745, ISSN 2072-6694
DOI: 10.3390/cancers13040745