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Ultrasound Cavitation in Soft Materials

Objective

The pressures and temperatures developing during the interactions of shockwaves with cavitation bubbles and soft matter induce complex phenomena, both at physical and biochemical levels. These have a non- exhaustive range of relevant applications including ultrasound-based therapies, surface cleaning and food processing. Our aim is to explore these processes both in micro and macroscales using experiments and to develop new computational capabilities for their simulations. Measurements will include temperature/ species forming in collapsing bubbles, identifying chemical reactions and possible tissue interaction, such as protein denaturation and agglomeration; tissue cavitation threshold and its control using nanoparticles, allowing development of new cavitation-mimicking-tissue materials extrapolating to actual tissue properties that will be used for in-vitro testing of equipment with minimum collateral damages. Computations will be based on advanced multi-resolution methods coupling fluid flow, chemical reactions and deforming material mechanics solvers, with physically consistent thermodynamic closure models for the involved materials; pressure wave propagation, bubble nucleation and material damage effects will link microscale phenomena to macroscale. Uncertainty quantification techniques will link computations with experimental data. UCOM builds upon the strong foundations of the PIs and their teams in training researchers in computational and experimental methods on cavitation and their strong record to successfully integrate research and technical applications. The final goal of the research and training program is to explore the enormous potential of the new and experimentally validated computational tools to guide breakthrough innovations and high-impact, high-tech technologies ranging across different sectors that all eventually enhance their careers and will be serving the well-being.

Field of science

  • /natural sciences/physical sciences/acoustics/ultrasound

Call for proposal

H2020-MSCA-ITN-2018
See other projects for this call

Funding Scheme

MSCA-ITN-ETN - European Training Networks

Coordinator

CITY UNIVERSITY OF LONDON
Address
Northampton Square
EC1V 0HB London
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 909 517,68

Participants (7)

TECHNISCHE UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 252 788,40
Address
Arcisstrasse 21
80333 Muenchen
Activity type
Higher or Secondary Education Establishments
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Switzerland
EU contribution
€ 562 553,28
Address
Batiment Ce 3316 Station 1
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
SORBONNE UNIVERSITE
France
EU contribution
€ 549 604,08
Address
21 Rue De L'ecole De Medecine
75006 Paris
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT TWENTE
Netherlands
EU contribution
€ 796 859,64
Address
Drienerlolaan 5
7522 NB Enschede
Activity type
Higher or Secondary Education Establishments
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
United Kingdom
EU contribution
€ 606 345,12
Address
Old Brompton Road 123
SW7 3RP London
Activity type
Higher or Secondary Education Establishments
OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG
Germany
EU contribution
€ 252 788,40
Address
Universitaetsplatz 2
39106 Magdeburg
Activity type
Higher or Secondary Education Establishments
UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 281 276,64
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments

Partners (9)

UNIVERSITY OF WASHINGTON
United States
Address
Brooklyn Avenue Ne 4333
98195 9472 Seattle Wa
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN
United States
Address
South Street 3003 1068
46109 1274 Ann Arbor
Activity type
Higher or Secondary Education Establishments
TSINGHUA UNIVERSITY
China
Address
Qing Hua Yuan
100084 Beijing
Activity type
Higher or Secondary Education Establishments
NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO
Japan
Address
Hongo Bunkyo Ku 7 3 1
113 8656 Tokyo
Activity type
Higher or Secondary Education Establishments
AVIGNON UNIVERSITE
France
Address
Rue Louis Pasteur 74
84029 Avignon Cedex 01
Activity type
Higher or Secondary Education Establishments
KING'S COLLEGE LONDON
United Kingdom
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
GUYS AND ST THOMAS' NHS FOUNDATIONTRUST
United Kingdom
Address
Westminster Bridge Road
SE1 7EH London
Activity type
Research Organisations
PRECISION ACOUSTICS LIMITED
United Kingdom
Address
South Terrace - South Street 4
DT1 1DE Dorchester
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
DORNIER MEDTECH SYSTEMS GMBH
Germany
Address
Argelsrieder Feld 7.
82234 Wessling
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)