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MEFISTO - Meniscal functionalised scaffold to prevent knee Osteoarthritis onset after meniscectomy

Project description

An innovative meniscus scaffold against osteoarthritis

Meniscal resection often leads to early osteoarthritis (OA), which necessitates alternative reconstructive strategies. The EU-funded MEFISTO project proposes to develop a functionalised nanomaterial-based scaffold capable of interacting with the native meniscal tissue. This innovative device will promote local revascularisation and help regenerate the native meniscus, especially in younger patients. At the same time, it will deliver drugs locally to modulate tissue inflammation in patients with advanced OA. Given the considerable number of individuals undergoing meniscectomy, the MEFISTO interventions will improve surgery outcomes and reduce OA-related co-morbidities.

Call for proposal

H2020-NMBP-TR-IND-2018-2020

See other projects for this call

Sub call

H2020-NMBP-TR-IND-2018

Coordinator

GEISTLICH BIOMATERIALS VERTRIEBSGESELLSCHAFT MBH
Net EU contribution
€ 37 500,00
Address
Schneidweg 5
76534 Baden-baden
Germany
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Baden-Württemberg Karlsruhe Baden-Baden, Stadtkreis
 

Participants (13)

Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

GEISTLICH PHARMA AG
Switzerland
Net EU contribution
€ 323 750,00
Address
Bahnhofstrasse 40
6110 Wolhusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Schweiz/Suisse/Svizzera Zentralschweiz Luzern
 
HUMANITAS UNIVERSITY
Italy
Net EU contribution
€ 847 375,00
Address
Via Rita Levi Montalcini Snc
20090 Pieve Emanuele
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KLINIKUM DER UNIVERSITAET REGENSBURG
Germany
Net EU contribution
€ 543 750,00
Address
Frans Josef Strauss Allee 11
93053 Regensburg
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Bayern Oberpfalz Regensburg, Kreisfreie Stadt
TISSUE CLICK LTD
United Kingdom
Net EU contribution
€ 381 250,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
28 Sycamore Close
BN2 6SJ Brighton
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
South East (England) Surrey, East and West Sussex Brighton and Hove
 
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
Spain
Net EU contribution
€ 482 197,50
Address
Colexio De San Xerome Praza Do Obradoiro S/n
15782 Santiago De Compostela
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITEIT ANTWERPEN
Belgium
Net EU contribution
€ 498 562,50
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 461 875,00
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ORTHOKEY ITALIA SRL
Italy
Net EU contribution
€ 253 125,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Piazza Nazioni Unite 15
54033 Carrara Ms
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Centro (IT) Toscana Massa-Carrara
 
ETABLISSEMENT FRANCAIS DU SANG
France
Net EU contribution
€ 216 875,00
Address
Avenue Du Stade De France 20
93210 La Plaine Saint Denis
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
Region
Ile-de-France Ile-de-France Seine-Saint-Denis
 
ACTIVE IMPLANTS BV
Netherlands
Net EU contribution
€ 852 762,50
Address
Zijlweg 148B 0301, 3Hg
2015 BJ Haarlem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
West-Nederland Noord-Holland Agglomeratie Haarlem
 
AIM GMBH - ASSESSMENT IN MEDICINE RESEARCH AND CONSULTING
Germany
Net EU contribution
€ 248 125,00
Address
Marie Curie Str. 8
79539 Lorrach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Baden-Württemberg Freiburg Lörrach
 
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 559 442,50
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
SCIPROM SARL
Switzerland
Net EU contribution
€ 290 000,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Rue Du Centre 70
1025 Saint Sulpice
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud