Post-transcriptional regulation of effector function in T cells by RNA binding proteins

Project Information

PRinTERs

Grant agreement ID: 817533

DOI

10.3030/817533

Project closed

EC signature date 28 February 2019

Start date 1 March 2019

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

Stichting Sanquin Bloedvoorziening
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Data management plan

Publications

Other (2)

mTOR signaling promotes cytokine production in T cells through 3UTR-mediated translation control

Author(s): Anouk P. Jurgens, Josephine Zwijnen, Floris P.J. Van Alphen, Antonia Bradaric, Koos Rooijers, Arie Jan Hoogendijk, Branka Popovic, Monika C. Wolkers
Published in: pre-print, Issue 6, 2024
Publisher: Cold spring harbor
DOI: 10.1101/2024.10.01.616022

Learning the sequence code of protein expression in human immune cells

Author(s): Benoît P. Nicolet, Anouk P. Jurgens, Kaspar Bresser, Aurélie Guislain, Antonia Bradariç, Monika C. Wolkers
Published in: pre-print, under review, Issue 5, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.09.01.555843

Peer reviewed articles (6)

Sequence determinants as key regulators in gene expression of T cells

Author(s): Benoit P. Nicolet, Nordin D. Zandhuis, V. Maria Lattanzio, Monika C. Wolkers
Published in: Immunological Reviews, 2021, ISSN 0105-2896
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/imr.13021

Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

Author(s): Branka Popović, Benoît P. Nicolet, Aurélie Guislain, Sander Engels, Anouk P. Jurgens, Natali Paravinja, Julian J. Freen-van Heeren, Floris P.J. van Alphen, Maartje van den Biggelaar, Fiamma Salerno, Monika C. Wolkers
Published in: Cell reports, 2024, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1101/2021.11.03.467112

Dynamic Post-Transcriptional Events Governing CD8+ T Cell Homeostasis and Effector Function

Author(s): Fiamma Salerno, Martin Turner, Monika C. Wolkers
Published in: Trends in Immunology, Issue 41/3, 2020, Page(s) 240-254, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2020.01.001

Regulation of IFN‐γ production by ZFP36L2 in T cells is time‐dependent

Author(s): Nordin D. Zandhuis, Aurélie Guislain, Abeera Popalzij, Sander Engels, Branka Popović, Martin Turner, Monika C. Wolkers
Published in: European Journal of Immunology, 2024, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202451018

T cells at work: How post‐transcriptional mechanisms control T cell homeostasis and activation

Author(s): Anouk P. Jurgens,Branka Popović, and Monika C. Wolkers
Published in: European Journal of Immunology, 2021, ISSN 1521-4141
Publisher: Wiley
DOI: 10.1002/eji.202049055

The relationship of mRNA with protein expression in CD8⁺T cells associates with gene class and gene characteristics

Author(s): Benoît P. Nicolet, Monika C. Wolkers
Published in: Plos One, 2024, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1101/2020.04.21.053884

Non-peer reviewed articles (1)

RNA-binding protein expression alters upon differentiation of human B cells and T cells

Author(s): N.Zandhuis, BP nicolet, MC Wolkers
Published in: BioRxiv (Frontiers in immunology- accepted), 2021, ISSN 2692-8205
Publisher: CSHL
DOI: 10.1101/2021.06.10.447413