An innovative approach for delivering brain therapeutics
Our understanding of the brain and of neuropsychiatric and neurological disorders is impeded by the lack of non-invasive methods for measuring neural circuits. The EU-funded EngineeringBAP project is working on innovative technologies that will allow large-scale single-neuron resolution measurements as well as the modulation of neural circuits through the precise delivery of neuromodulators. As a proof-of-principle, scientists have already corrected brain abnormalities in mutant zebrafish, through the localised delivery of a neuromodulator cocktail. The work will help study brain activity in detail and characterise the circuit dysfunctions associated with neurological disorders, thereby paving the way for improved treatments.
Fields of science
Funding SchemeERC-COG - Consolidator Grant
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