An innovative approach for delivering brain therapeutics
Our understanding of the brain and of neuropsychiatric and neurological disorders is impeded by the lack of non-invasive methods for measuring neural circuits. The EU-funded EngineeringBAP project is working on innovative technologies that will allow large-scale single-neuron resolution measurements as well as the modulation of neural circuits through the precise delivery of neuromodulators. As a proof-of-principle, scientists have already corrected brain abnormalities in mutant zebrafish, through the localised delivery of a neuromodulator cocktail. The work will help study brain activity in detail and characterise the circuit dysfunctions associated with neurological disorders, thereby paving the way for improved treatments.
Fields of science
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