Project description
Cell mimicry for liver engineering as a replacement for a liver transplant
The global spread of obesity and type 2 diabetes has resulted in the prevalence of medical conditions such as the non-alcoholic fatty liver disease that causes liver failure and requires liver transplantation. The EU-funded ArtHep project proposes tissue engineering for the assembly of hepatic-like tissue, consisting of biological and synthetic entities mimicking the structure elements and functions of the liver. The integrated biocatalytic subunits will slow down liver damage, and the micro-environment in the bioprinted tissue will facilitate the connection between the transplant and the liver. The project will provide the foundation to counterbalance the increasing demand for donor livers.
Fields of science
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesclinical medicineendocrinologydiabetes
- engineering and technologymaterials engineeringcoating and films
- medical and health sciencesclinical medicinehepatology
- medical and health scienceshealth sciencesnutritionobesity
Programme(s)
Funding Scheme
ERC-COG - Consolidator Grant
Host institution
8000 Aarhus C
Denmark
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Beneficiaries (1)
8000 Aarhus C
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