Securing Adoption of Personalised Health in REgions

Project Information

SAPHIRE

Grant agreement ID: 825046

DOI 10.3030/825046

Project closed

EC signature date 14 November 2018

Start date 1 December 2018

End date 31 May 2022

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 1 853 813,13

EU contribution € 1 778 813,00

Coordinated by

VLAAMSE GEWEST
Belgium

Deliverables

Documents, reports (15)

Dissemination materials

Development and production of tailored dissemination materials M1 M36This task will include the production ofProject leaflet One project leaflet or bookmarkonepager presenting the projects main elements will be available early in the project to be distributed by partners through their networks and at eventsPress release Press releases in EN at project start and later on the project results will be sent to the European press and national journalists the latter with the help of partners Articles on the project results will be published on the SAPHIRE website The articles and related picture materials will be made available to all regions for inclusion in their respective contactsnetworksEnewsletters all partners A regular enewsletter will be created and disseminated through the network of all partners and of the website including the outreach to relevant networks including the initiatives listed in section 13 but also ICPerMed EC DGs SANTE RTD and JRC Science Europe European Foresight Platform IMI2 JU JPI HDHL JPND Innovation and Science Policy Experts RISE high level group HLG Virtual Institute of Responsible Innovation VIRI ERANETs ERALEARN ERA PerMed RADIORG ESMO CancerNet Infographics to support engagement with targeted stakeholders A specific section about the project will be created on the website as well as on partners website to drive traffic to the project website The textpicture materials will be made available to all regions for inclusionadaptation for their respective websitesSocial media Using the channels and networks of other partners different platforms eg Facebook Twitter LinkedIn will be used to target the respective stakeholder groups The Twitter account dedicated to PM related news will also be used to disseminate project results The aim of the social media strategy will be to build an engaged community Videos will be produced throughout the project to highlight project outputs and for communication and engagement purposes The videos will be hosted on a dedicated SAPHIRe Youtube channel the SAPHIRe website and will be shared via Twitter and LinkedIn in order to achieve maximum impact

University hospitals and of regional hospitals and other regional actors

Policy brief on the role of university hospitals and of regional hospitals and other regional actors Identification of relevant stakeholders and their needs M 621The inventory created in WP2 will identify the different regional stakeholders and will bring a general insight in the current state of play with respect to PM in these regions To address specific needs to implement PM in different regions dedicated workshops are envisioned to get answers on specific questions The issues distilled from the analyses in WP2 will be introduced by issues papers which will provide a basis for discussions during the workshops In addition feedback on these issues papers and further input from workshop participants will be asked prior to the workshops The outcome of discussions in the workshops will be summarised in policy briefs that will be published on the website of the project In a first phase workshops are envisioned on Regional needs and barriers interfering with PM implementations How can we address theseIdentifying regulatory needs what can regions provide What are specific regulatory needs for different regionsThe role of university hospitals and of regional hospitalsIdentifying specific needs in different regions and specifically in sparsely populated regions NorthSouth EastWest EU13How to translate science in applications industry involvementBecause of the corona pandemic the initially workshops planned will be replaced by online versions The workshops were planned to be 2 half days events and will be replaced by 2 or 3 webinars of 2 hours

Regional ecosystems

Report summarising the information gathering from desk research: Regional ecosystems and frameworks for PM. WP2 entails the gathering and processing of relevant information concerning PM in regions: policies, research infrastructure, funding instruments, best practices of adoption, healthcare system, intra- and interregional collaborations, etc. To identify regional ecosystems and frameworks for research, innovation and adoption of PM. This will be done by means of: • Desk research: i.a. making use of the various databases related to regions and biomedical clusters (e.g. RIS3 platform, Interreg, Eurostat, Innovation Scoreboards, CORDIS, European Cluster Collaboration Platform, European Observatory for clusters and industrial change, etc.) • Interviews with existing associations/networks of regions, national and regional representatives in Brussels, ICPerMed members, running collaborative projects and partnerships, etc.

PM profiles

Report on regional PM profiles (SWOT) including forward look. WP2 will particularly focus on joint SWOT-analyses with regions to establish their current position as well as a forward look per region to implement PM. The Stakeholders’ Platform will include different communities active to implement PM in collaborative efforts and at different levels (interregional, cross-border). The specific aim is to reach out to regional stakeholders to verify the state of the affairs regarding PM (SWOT) and to establish their demand articulation (unmet needs) in the (future) adoption of PM in the region. In collaboration with WP4 and WP5, a Stakeholders’ Platform built around different communities will be established for consultation and information exchange

engagement with stakeholders

Plan for the sustainable engagement with stakeholders There is a need to find innovative ways of targeting and communicating with relevant stakeholders at multiple regional national European levels to keep them sustainably engaged in the SAPHIRE platform This task will develop and execute a plan to establish lasting engagement to support the emerging SAPHIRE Stakeholders Platform and to ensure continued engagement with relevant stakeholder groups beyond the duration of the project There will be a close collaboration with WP2 mapping workshop and database open consultation and WP34 strategy and platform building as well as with the other ongoing PM initiatives Specific communication materials will be developed for support The project goal of creating an Interregional PM Portal may find its host structures in the ICPerMed including sustainable communication platforms accessible beyond the lifetime of the project

Recommendations on the implementation of PM in regions based on case studies

Case studies on best practice of PM implementation M12 M36Case studies will be used to produce a set of best practice procedures for a fruitful implementation of PM research into realworld applications These case studies will be accessible for all target groups via the website and presented within task 56 These case studies summarise the most important results derived from the discussions and work within the Work Packages A workshop organised in M15 is to lay the basis for this task

Communication and dissemination plan

Development and implementation of the communication and dissemination plan: A ‘Communication and Dissemination Plan’ will be developed in consultation with the other partners, defining key messages, target audiences (input from WP2), and selecting appropriate tools and channels (including those of other partners). It will draw on the networks, communication channels and vehicles of the partners and the Stakeholders’ Platform. The plan includes a strategy for engaging with and monitoring social media.

Recommendations for alignment and usage of structural funds

Report on recommendations for alignment and usage of structural funds Activation and Acceleration M1836Projects identified through the community building and matchmaking platform in Task 41 will be recommended for funding or investments through the relevant financial instruments available which include the EU framework programme ESIF or EIB instruments The outcome of the activities may serve as input for an investment agenda such as to feed into a smart specialisation strategy for PM and addressing different financial instruments as appropriate and as an agenda towards the next framework programme to further PM across all European regions

Specific needs in different regions and specifically in sparsely populated regions

Policy brief on specific needs in different regions and specifically in sparsely populated regions NorthSouth EastWest EU13 Identification of relevant stakeholders and their needs M 621The inventory created in WP2 will identify the different regional stakeholders and will bring a general insight in the current state of play with respect to PM in these regions To address specific needs to implement PM in different regions dedicated workshops are envisioned to get answers on specific questions The issues distilled from the analyses in WP2 will be introduced by issues papers which will provide a basis for discussions during the workshops In addition feedback on these issues papers and further input from workshop participants will be asked prior to the workshops The outcome of discussions in the workshops will be summarised in policy briefs that will be published on the website of the project In a first phase workshops are envisioned on Regional needs and barriers interfering with PM implementations How can we address theseIdentifying regulatory needs what can regions provide What are specific regulatory needs for different regionsThe role of university hospitals and of regional hospitalsIdentifying specific needs in different regions and specifically in sparsely populated regions NorthSouth EastWest EU13How to translate science in applications industry involvementBecause of the corona pandemic the workshops initiallyplanned will be replaced by online versions The workshops were planned to be 2 half days events and will be replaced by 2 or 3 webinars of 2 hours

Translate science in applications - industry involvement

Policy brief on how to translate science in applications industry involvement Identification of relevant stakeholders and their needs M 621The inventory created in WP2 will identify the different regional stakeholders and will bring a general insight in the current state of play with respect to PM in these regions To address specific needs to implement PM in different regions dedicated workshops are envisioned to get answers on specific questions The issues distilled from the analyses in WP2 will be introduced by issues papers which will provide a basis for discussions during the workshops In addition feedback on these issues papers and further input from workshop participants will be asked prior to the workshops The outcome of discussions in the workshops will be summarised in policy briefs that will be published on the website of the project In a first phase workshops are envisioned on Regional needs and barriers interfering with PM implementations How can we address theseIdentifying regulatory needs what can regions provide What are specific regulatory needs for different regionsThe role of university hospitals and of regional hospitalsIdentifying specific needs in different regions and specifically in sparsely populated regions NorthSouth EastWest EU13How to translate science in applications industry involvementBecause of the corona pandemic the workshops initially planned will be replaced by online versions The workshops were planned to be 2 half days events and will be replaced by 2 or 3 webinars of 2 hours

Community building

Final report on the Round Table eventsShowcasing best practices M630a As PM is a most promising field for innovation the InnoStars network will be used to reach out to regions interested to embrace PM in their innovation strategies and strive to implement PM To facilitate collaboration InnoStars supported by PHA will present best practices and groundbreaking technologies based on the WP2 and WP3 results in socalled Smart Technology Mix round table online events The aim of these events is to disseminate latest technological achievements to foster industryhealthcare providers and industryuniversity cooperation to stimulate the implementation of new technologies in the field of PM An intelligent matchmaking tool will be used to help stakeholders finding potential project partners at early stagesb For the more advanced regions and collaborations the S3Platform methodology will be a startingpoint The connection with ICPerMed and the regions involved as well as with the actors active in ERA PerMed on the one hand and the connection with smart specialisation initiatives in the area of PM on the other hand will further feed the collection of best practice examples of how to successfully implement PM In the first instance connecting to the smart specialisation platform on Medical Technologies was at the moment of writing be the most relevant However a complementary smart specialisation platform on PM started may be initiated if an expression of interest for such a platform recently and is also coordinated by the coordinator of SAPHIRE will be awarded c Regions with best practice examples will act as mentors to those who wish to avail of trainingmentorship opportunities in order to introduce similar personalised medicine initiatives in their region This knowledge transfer will be achieved through a series of online workshops Through the mentorship training programme attendees will gain practical advice from experts who have experience in implementing PM initiatives in their region

Roadmap for regions

A modular roadmap for regions to implement PM including best practice recommendations Together with the input from WP2 WP4 and WP5 case studies the outcomes of the different workshops and webinars will ultimately allow to draw a roadmap addressing the specific needs in the different types of European regions to develop PM In consultation with ICPerMed and its partners in ERAPerMed and with the EU a summarising workshop gathering experts with different backgrounds from the Stakeholders Platform representing the different communities will be organised to crystalise from the WPs outcomes the basis for a modular strategic roadmap including recommendations on best practices to implement PM at regional level The roadmap should also take into account the different authority levels that are relevant for the implementation of PM This modular roadmap for regions at different levels of implementation of PM will not only serve as an inspiration for the regional authorities interested it may also serve as input for the next framework programme to bring PM to reality in all European regions This process will also provide input for WP4 on how collaborations between regions and cluster organisations academia industry and regulatory bodies could be improved and on needs for funding or investments through the appropriate financial instrumentsThe format of the workshops or webinars is to gather around 20 expert participants to discuss on the basis of a discussion paper fed with input from the desktops research and prior input from the experts

Regulatory needs and opportunities

Policy brief of regulatory needs and opportunities in regions Identification of relevant stakeholders and their needs (M 6-21) The inventory created in WP2 will identify the different regional stakeholders and will bring a general insight in the current state of play with respect to PM in these regions. To address specific needs to implement PM in different regions dedicated workshops are envisioned to get answers on specific questions. The issues, distilled from the analyses in WP2, will be introduced by ‘issues papers’ which will provide a basis for discussions during the workshops. In addition, feedback on these issues papers and further input from workshop participants will be asked prior to the workshops. The outcome of discussions in the workshops will be summarised in policy briefs that will be published on the website of the project. In a first phase, workshops are envisioned on: • Regional needs and barriers interfering with PM implementations; How can we address these? • Identifying regulatory needs: what can regions provide? What are specific regulatory needs for different regions? • The role of university hospitals and of regional hospitals • Identifying specific needs in different regions and specifically in sparsely populated regions (North-South; East-West (EU-13)) • How to translate science in applications – industry involvement

Barriers and needs

Policy brief on barriers and needs interfering with PM implementations and how to overcome these Identification of relevant stakeholders and their needs (M 6-21) The inventory created in WP2 will identify the different regional stakeholders and will bring a general insight in the current state of play with respect to PM in these regions. To address specific needs to implement PM in different regions dedicated workshops are envisioned to get answers on specific questions. The issues, distilled from the analyses in WP2, will be introduced by ‘issues papers’ which will provide a basis for discussions during the workshops. In addition, feedback on these issues papers and further input from workshop participants will be asked prior to the workshops. The outcome of discussions in the workshops will be summarised in policy briefs that will be published on the website of the project. In a first phase, workshops are envisioned on: • Regional needs and barriers interfering with PM implementations; How can we address these? • Identifying regulatory needs: what can regions provide? What are specific regulatory needs for different regions? • The role of university hospitals and of regional hospitals • Identifying specific needs in different regions and specifically in sparsely populated regions (North-South; East-West (EU-13)) • How to translate science in applications – industry involvement

Complementarities to implement PM

Report on complementarities across regions and specific prioritised themes for interregional collaboration to implement PM Establishing collaboration potential through analysis and mapping: • Seeking opportunities for (inter)regional collaboration by identifying ‘smart’ complementarities in the PM value chain. • Identification, selection and prioritisation of topics suitable for scoping workshops (in collaboration with WP3 and WP4).

Open Research Data Pilot (1)

DMP

Data Management Plan (DMP) will be developed for data collected during the course of the project to be stored and made findable, accessible, interoperable and re-usable (FAIR). The DMP will include information on the handling of research data during & after the end of the project; what data will be collected, processed and/or generated; which methodology & standards will be applied; whether data will be shared/made open access; and how data will be curated & preserved (including after the end of the project).

Websites, patent fillings, videos etc. (2)

Online database on PM implementation in EU regions

Online database giving information on PM implementation in EU regions the database will provide access to the data gathered in WP2.

Project website

Development of project identity, templates and website (M1- M6) • Branding: project identity, graphic line and logo: A project identity, logo and templates will be created, capturing the vision of the project. • Project website: A specific website (www.saphire.eu) for the project will be set up and maintained for the duration of the project (+3 years after the project). It will include: o External website: main project information resource (objectives, partners, work areas, WP2 database, relevant PM news and developments, social media links, and project results), and means of communication. o An internal platform intranet (restricted area) for communication and document repository.