Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS

INCALO: Internal black carbon loading: validation of a novel biomarker

Project description

Novel black carbon detections

Industries, households cars and trucks emit complex mixtures of air pollutants, many of which are detrimental to health. Air pollution-related health costs alone have been estimated at USD 1.6 trillion, according to the World Health Organisation (WHO). INCALO has developed a novel method to detect carbonaceous nano-particles in the urine of healthy children. The so-called ENVIRONAGE project has demonstrated its usefulness as individual long-term exposure markers. This pioneering study is of innovative value, paving the way for a non-invasive assessment of long-term individual exposure to one of the most toxic air pollutants, black carbon. The findings of the project will also hugely assist in epidemiological investigations and biomonitoring studies.

Objective

Ambient air pollution, including black carbon, entails a serious public health risk because of its carcinogenic potential and as climate pollutant. Inhalation of fossil fuel-derived particulate matter (PM) is associated with a wide range of non-pulmonary health effects. Based on the WHO report of 2015 the European health annual costs of air pollution have been estimated to US$ 1.6 trillion. Although recent studies strongly suggest that particle translocation in biological systems is biologically plausible, they do not prove that ambient fossil fuel-derived carbonaceous nanoparticles enter the human systemic circulation in real-life conditions. We developed a novel method to detect carbonaceous nanoparticles in the urine of healthy children. The ERC funded ENVIRONAGE project already made a strong case for promoting urinary carbon detection to practice by demonstrating its usefulness as individual long-term exposure marker. Taking advantage of white-light generation by carbonaceous nanoparticles under femtosecond pulsed laser illumination, we demonstrated the presence of these particles in urine and its relation with the external environmental air pollution (Saenen et al. Am J Respir & Crit Care Med, in press). This pioneering study is of innovative value, as it paved the way for a non-invasive assessment of long-term individual exposure to one of the most toxic air pollutants, black carbon, and will be useful in epidemiological investigations, biomonitoring studies as well as in occupational settings. The aim of the INCALO (INternal black CArbon LOading) project is to promote the output of the ENVIRONAGE project towards a process for facilitation and commercialization of internal markers of exposure to black carbon.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

You need to log in or register to use this function

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-POC - Proof of Concept Grant

See all projects funded under this funding scheme

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2018-PoC

See all projects funded under this call

Host institution

UNIVERSITEIT HASSELT
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 149 170,00
Address
MARTELARENLAAN 42
3500 Hasselt
Belgium

See on map

Region
Vlaams Gewest Prov. Limburg (BE) Arr. Hasselt
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 149 170,00

Beneficiaries (1)

My booklet 0 0