Project description
Preventing the formation of surgical adhesions
Surgical adhesions are scar tissue that abnormally joins organ surfaces together as a post-operative or post-injury complication. They emerge because the body attempts to repair itself and may lead to adverse effects as well as repeat surgeries. The EU-funded FuseX project has developed an innovative system that minimises the chance of adhesion formation during surgery. The approach entails the administration of naturally occurring coagulation factors and proteins from donor blood plasma prior to wound closing. Implementation of the FuseX system has the potential to reduce adhesion formation after abdominal and gynaecological operations.
Objective
Surgical adhesions are a consequence of abdominal trauma during surgery. Although there are a multitude of available barriers on the market today, the efficacy of these solutions is still in question and can lead to adverse side effects. If untreated, these surgical adhesions can solidify and grow, potentially leading to infertility, chronic pain, and difficulties in repeat operations. To address adhesions, patients must undergo additional abdominal surgery, putting unnecessary stress on existing healthcare systems. On average, 35% of patients who undergo open abdominal or pelvic surgery are readmitted twice in the following 10 years due to complications.
EIO Biomedical has developed a revolutionary anti-adhesion system in order to eliminate initial formation of surgical adhesions. The FuseX system, delivers a mixture of donor blood plasma with a concentrated mix of natural coagulation factors found in the blood. This results in less post-surgical adhesions, and related complications, and translates to an estimated 6-12 B€ in saved expenses per year. Preliminary testing of the material demonstrated a 60-90% reduction of adhesions, depending on the severity, whilst the non-invasive laparoscopic application also reduced open wound size and extent of trauma. During the phase 1 project, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. Within the overall innovation project, EIO Biomedical is set to initiate safety and efficiency trials in Lithuania and Spain, where they will initially market their product. After initial testing, device function and efficiency will be further improved to enable a more rapid procedure for scale up to commercialization. Post-commercialization, CEO Dr. Yair Pilpel hopes to integrate anti-inflammatories, pain killers, and antibiotics, into the solution for widespread use in hospitals, clinics, and potentially schools.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
17111 NAZARETH
Israel
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.