Project description
A protective device against embolism
Aortic valve diseases may require surgical replacement of the defective valve. This is often performed through a procedure known as transcatheter aortic valve implantation (TAVI), which involves the insertion of a catheter into a blood vessel to reach the heart and fix the valve. However, TAVI carries the risk of releasing embolic particles from the natural aortic valve to the blood flow which can reach the brain or other organs, with debilitating consequences. The key objective of the EU-funded Filterlex project is to prevent such complications and reduce the risk of stroke during catheter-based structural heart procedures. To that end, the project has developed a protective device that is placed on the aorta during the TAVI procedure to capture and remove embolic particles.
Objective
Aortic stenosis is the most common and most serious heart valve problem. It leads to shortness of breath, angina, blackouts and in severe cases: sudden death. This condition presents 2-9% of general population over 65 years old. Trans-catheter aortic valve implantation (TAVI) is a standard therapeutic option for patients with severe aortic stenosis condition. However, during maneuvering, positioning and deployment of the new valve using catheter, embolic particles are released from the natural aortic valve to the vascular system, making TAVI procedure unsafe. Filterlex is a novel intra-aortic protection device for deflecting, capturing and removing embolic particles during catheter-based left-heart procedures. Easily positioned, deployed and retrieved, the device provides complete celebral protection during valve implantation. The device provides full body protection from embolic showers, and thus, makes TAVI procedure safe.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.3. - PRIORITY 'Societal challenges
See all projects funded under this programme -
H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3089900 CAESAREA
Israel
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.