Skip to main content

Modulating skin innervation to treat cutaneous inflammation

Project description

Targeting skin innervation for psoriasis treatment

Skin diseases are the most common human illnesses, with a third of the world population affected at any given time. The EU-funded NEUROSKIN project aims to determine how different skin innervations affect psoriasis, representing the largest class of skin conditions mediated by inflammation. The research will utilise a transgenic mouse model that enables optogenetic control of local peripheral innervations using light. The NEUROSKIN will take advantage of this tool to develop additional transgenic models relevant to cutaneous neuronal subpopulations. The models will allow control of the activity of neurons innervating the psoriatic plaques at different stages of the disease, providing potential new neuronal targets for interventions to treat inflammatory skin conditions.

Call for proposal

ERC-2018-PoC
See other projects for this call

Host institution

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Address
Senate Building Technion City
32000 Haifa
Israel
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 150 000

Beneficiaries (1)

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel
EU contribution
€ 150 000
Address
Senate Building Technion City
32000 Haifa
Activity type
Higher or Secondary Education Establishments