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Bioactive lipids at the ocular surface: from Langmuir surface balance to ophthalmic nanoemulsions

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Publications

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis

Author(s): Georgi A. Georgiev, Mohammad Sharifian Gh., Jeff Romano, Karina L. Dias Teixeira, Craig Struble, Denise S. Ryan, Rose K. Sia, Jay P. Kitt, Joel M. Harris, Ku-Lung Hsu, Adam Libby, Marc G. Odrich, Tatiana Suárez, Robert L. McKown, Gordon W. Laurie
Published in: Journal of Biological Chemistry, Issue 296, 2021, Page(s) 100070, ISSN 0021-9258
DOI: 10.1074/jbc.ra120.015833

A spectroscopic study of the composition and conformation of cholesteryl and wax esters purified from meibum

Author(s): Anthony Ewurum, Akhila Ankem, Georgi Georgiev, Douglas Borchman
Published in: Chemistry and Physics of Lipids, Issue 238, 2021, Page(s) 105088, ISSN 0009-3084
DOI: 10.1016/j.chemphyslip.2021.105088

Improving Stability of Tear Film Lipid Layer via Concerted Action of Two Drug Molecules: A Biophysical View

Author(s): Petar Eftimov, Agnieszka Olżyńska, Adéla Melcrová, Georgi As. Georgiev, Philippe Daull, Jean-Sebastien Garrigue, Lukasz Cwiklik
Published in: International Journal of Molecular Sciences, Issue 21/24, 2020, Page(s) 9490, ISSN 1422-0067
DOI: 10.3390/ijms21249490

Interactions of Meibum and Tears with Mucomimetic Polymers: A Hint towards the Interplay between the Layers of the Tear Film

Author(s): Petar Eftimov, Norihiko Yokoi, Ana M. Melo, Philippe Daull, Georgi As. Georgiev
Published in: International Journal of Molecular Sciences, Issue 22/5, 2021, Page(s) 2747, ISSN 1422-0067
DOI: 10.3390/ijms22052747