An integrated high-throughput human cell and Drosophila screening platform for the expedited discovery of anti-ageing compounds

Project Information

AgePhagy

Grant agreement ID: 842174

DOI

10.3030/842174

Project closed

EC signature date 26 March 2019

Start date 1 April 2019

End date 30 September 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 149 872,00

EU contribution

€ 149 872,00

Coordinated by

UNIVERSITY COLLEGE LONDON
United Kingdom

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Agephagy – Adapting Autophagy for Health During Aging

Author(s): Eleanor R. Stead, Jorge I. Castillo-Quan, Victoria Eugenia Martinez Miguel, Celia Lujan, Robin Ketteler, Kerri J. Kinghorn, Ivana Bjedov
Published in: Frontiers in Cell and Developmental Biology, Issue 7, 2019, ISSN 2296-634X
Publisher: Nature Publishing Group
DOI: 10.3389/fcell.2019.00308

The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation

Author(s): Ivana Bjedov , Charalampos Rallis
Published in: Genes, 2020, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes11091043

Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila

Author(s): Ivana Bjedov, Helena M. Cochemé, Andrea Foley, Daniela Wieser, Nathaniel S. Woodling, Jorge Iván Castillo-Quan, Povilas Norvaisas, Celia Lujan, Jenny Regan, Janne M. Toivonen, Michael P. Murphy, Janet Thornton, Kerri J. Kinghorn, Thomas P. Neufeld, Filipe Cabreiro, Linda Partridge
Published in: PLOS Genetics, Issue 16/11, 2020, Page(s) e1009083, ISSN 1553-7404
Publisher: Plos
DOI: 10.1371/journal.pgen.1009083

Non-peer reviewed articles (1)

A CellAgeClock for expedited discovery of anti-ageing compounds

Author(s): Celia Lujan, Eleanor J. Tyler, Simone Ecker, Amy P. Webster, Eleanor R. Stead, Victoria E. Martinez Miguel, Deborah Milligan, James C. Garbe, Martha R. Stampfer, Stephan Beck, Robert Lowe, Cleo L. Bishop, Ivana Bjedov
Published in: BioRxiv, 2020, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.1101/803676